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Pathogen of feigiophomycosis

, medical expert
Last reviewed: 23.04.2024
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Feogifomycosis - mycosis (pheomycotic cyst), caused by a number of demagogic (brown-pigmented) fungi, forming hyphae (mycelium) in tissues. Demacia fungi are brown-pigmented fungi, unlike nematocium fungi-hyalophomycetone (hyaline - non-pigmented hyphomycetes) forming a mycelium that cause hyalogomycosis. The demagogic fungi that cause feigiophomycosis are representatives of the genera Exophiala, Pbialaphora, Wangielta, Bipoiaris, Exscrohilum, Ctadophiahphora, Phaeoatmelhtnyccs, Altemaria, Aureobasidium, Cladosporium, Curvularia, Phoma.

Theophigomycosis develops after exposure to demagogic fungi from the soil in the microdamage of the skin of the extremities. A painless, drained mass is formed, which is necrotic, and a subcutaneous abscess develops. In the tissues, brown yeast-like cells, pseudohyf and hyphae are found. These fungi can cause opportunistic infections, including sinusitis (eg, Bipolaris, Exserohilum, Curvularia, Altemaria in patients with chronic allergic rhinitis or immunosuppression), and brain abscess with immunodeficiencies after inhalation of conidia. More often lesions of the brain cause the neurotropic fungus Cladophiatophora bantiana. When working with these fungi, special care must be taken.

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Microbiological diagnosis of feigiophomycosis

In skin scrapings, tissue biopsies or sputum treated with 10% KOH solution, brown septate hyphae are identified. They make crops on nutrient media such as Saburo - dextrose agar, where black colonies grow.

Treatment of feigiophomycosis

Surgical removal of affected areas is performed; prescribe amphotericin B, intraconazole, voriconazole.

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