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How is pneumococcal disease treated?
Last reviewed: 23.04.2024
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Indications for hospitalization
Patients with pneumococcal infection are hospitalized only according to clinical indications. Patients with suspicion of primary bacterial meningitis, pneumonia complicated by secondary meningitis, sepsis, endocarditis are sent to the infectious hospital. Patients with sinusitis, otitis media, complicated by meningitis need emergency surgery, therefore they are hospitalized in the ENT department.
Medication for pneumococcal infection
Antimicrobial treatment of pneumococcal infection depends on the clinical form of pneumococcal infection and the severity of the patient's condition.
When meningitis before the diagnosis is clarified, the treatment is carried out according to the scheme of empirical therapy of bacterial meningitis, after confirmation of the diagnosis - according to the scheme of treatment of pneumococcal meningitis.
The detoxification treatment of pneumococcal infection is carried out according to general principles. When meningitis apply osmotic and loop diuretics, dexamethasone 0.15 mg four times a day, according to indications - anticonvulsants, nootropic drugs, antioxidants.
Schemes of etiotropic therapy for pneumococcal meningitis
Strain of pneumococcus |
A drug |
Daily dose |
Multiplicity of administration per day |
The route of administration |
Penicillin-sensitive |
Benzylpe-nitsillin (the drug of choice) |
300-400 thousand units / kg |
6th |
Intramuscularly |
400-500 thousand units / kg |
8 |
Intravenously |
||
Cefotaxime (an alternative drug) |
200 mg / kg |
4 |
Intravenously |
|
Ceftriaxone (an alternative drug) |
100 mg / kg (not more than 4 g) |
1 |
Intravenously |
|
With intermediate resistance to penicillin |
Cefotaxime (the drug of choice) |
200 mg / kg |
4 |
Intravenously |
Ceftriaxone (the drug of choice) |
100 mg / kg (not more than 4 g) |
1 |
Intravenously |
|
Vancomycin (an alternative drug) vancomycin |
3 g, children 40 mg / kg 5-20 mg |
2 1 |
Intravenously Intravenously Endolumbular |
|
Meropenem (an alternative drug) |
3 g, children 40 mg / kg |
3 3 |
Intravenously Intravenously |
|
Resistant to penicillin |
Vancomycin (the drug of choice) + vancomycin |
3 g, children 40 mg / kg 5-20 mg |
3 1 |
Intravenously Intravenously Endolumbular |
Ceftriaxone (the drug of choice) |
4 g, children 100 mg kg |
1 |
Intravenously |
|
Cefotaxime (the drug of choice) |
12 g, children 200 mg / kg |
4 |
Intravenously |
|
Vancomycin |
5-20 mg |
1 |
Endolumbalno |
|
Meropenem (an alternative drug) |
Zg, children 40 mg / kg |
3 |
Intravenously Intravenously |
|
Linezolid (an alternative drug) |
12 grams |
2 |
Intravenously |
Diet
The regimen is determined by the clinical condition of the patient. A special diet is not required.
Approximate terms of incapacity for work
The period of incapacity for work is determined taking into account the clinical form of pneumococcal infection and the severity of the disease course. When meningitis, the average duration of incapacity for work is 2 months, while maintaining residual phenomena, a disability group is established.
Clinical examination
The neurologist spends a prophylactic medical examination for at least 1 year.
Patients who have transferred generalized forms of pneumococcal infection are advised to examine the immune status, avoid hypothermia, prevent flu and ARVI, and, on the recommendation of the physician, tempering procedures.
Treatment of pneumococcal infection should be combined with the following recommendations: after transferred meningitis, insolation, eating foods with a high salt content (herring, pickles), abundant drink, alcoholic beverages are contraindicated.