Diagnosis of Haemophilus Infections
Last reviewed: 23.04.2024
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Clinical diagnosis of hemophilic infection, except for epiglottitis, is indicative, since Hib is its most frequent pathogen. The diagnosis of Hib infection is established on the basis of the isolation of the pathogen culture and culture from pathological secrets (cerebrospinal fluid, pus, pleural effusion, sputum, swabs from the nasopharynx). In the latter case, only the isolation of capsular strains is of diagnostic significance. For seeding, use chocolate agar with growth factors. For diagnosis of meningitis, bacterioscopy, PCR and the reaction of RLA of the cerebrospinal fluid are also used.
[Differential diagnosis of hemophilic infection
Epiglottitis is differentiated from diphtheria of the upper respiratory tract, croup in ARVI and foreign body in the larynx. Other forms of Hib infection are distinguished on the basis of laboratory results.
Hib-meningitis is differentiated from other types of bacterial, viral meningitis, meningism in acute febrile illnesses.