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Vaccination against ku-fever
Last reviewed: 19.10.2021
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Ku-fever is a zoonosis, widespread, mainly in cattle-breeding regions. Called Coxiella burnetii, belonging to the γ-subgroup of Proteobacteria. Infection of a person occurs when contact with animals, the use of milk. Vaccination against ku-fever is carried out for persons at risk from the age of 14 to 60 years.
Vaccination against ku-fever is performed with the help of the Ku-fever vaccine - M-44 live dry cutaneous, Russia - lyophilized suspension of live culture of attenuated strain M-44 Coxiella burnetii, expressed in yolk sacs of chick embryos. Product: kit - ampoule of 0.5 ml (10 doses) + 1 ampoule 0.9% solution of sodium chloride. Packing 5 sets.
Reaction to administration and contraindications
On day 2-3, one-day malaise, chills, headache and a temperature of up to 37.5 ° are possible. Local reaction (no less than 90% of vaccinated): reddening and nodular swelling along the course of incisions lasting 3-4 days.
In addition to those common to live vaccines, contraindications are:
- allergic diseases (according to anamnesis): bronchial asthma, atopic dermatitis, pollinosis, allergy to chicken protein;
- chronic diseases of the upper respiratory tract and lungs;
- systemic connective tissue diseases;
Vaccination from fever is carried out no earlier than one month after the introduction of other vaccines. Possible simultaneous administration with brucellosis vaccine.
Vaccination schedule
It is injected once, by the skin of the methods of scarification through 2 drops (0.05 ml) of diluted vaccine at a distance of 30-40 mm on the outer surface of the middle third of the shoulder. Produce three cross-shaped incisions of 8-10 mm in length at a distance of 3-4 mm from each other with rubbing into the notches. Revaccination is administered at the same dose not earlier than 1 year after primary vaccination to persons whose serum lacks specific complement-binding antibodies.
A single injection of the vaccine is accompanied by the development of specific immunity 3-4 weeks after the inoculation with a duration of at least 1 year.
Store at 2-10 °, shelf life - 2 years.