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Treatment of enteropathogenic escherichiosis
Last reviewed: 19.10.2021
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Therapy of patients with enteropathogenic escherichiosis is built on the same principles as in other acute intestinal infections. Mandatory hospitalization is subject to patients with severe, and sometimes with moderate forms, requiring infusion therapy. Children with mild forms are treated at home. Children are also hospitalized for epidemics, newborns and those with severe concomitant diseases or complications.
Diet is prescribed taking into account the age of the child, feeding him to the disease, the severity and the period of the infectious process. The general principles of the diet are the same as in other acute intestinal infections. It should only be taken into account that EPE affects predominantly the small intestine, therefore, disturbances in digestion and digestion of food products are especially severe. Nevertheless, even with enteropathogenic escherichiosis, it is necessary to increase the amount of food sufficiently (after appropriate unloading) and introduce new foods into the diet, but as the functional state of the digestive tract recovers, preventing digestion.
Pathogenetic treatment of enteropathogenic escherichiosis assumes the urgent detoxification and restoration of hemodynamics by oral rehydration or intravenous infusion of missing quantities of fluid, electrolytes (1.5% reamberin solution) and other components in severe forms of the disease.
Of the means of etiotropic therapy for severe forms of the disease, especially with complications of bacterial nature (otitis media, pneumonia, etc.), prescribe antibiotics or chemotherapy drugs. Antibiotic therapy is also shown for moderate to severe forms in newborns and children of the first months of life because of the danger of generalization of the process. Assign polymyxin M, gentamicin, carbenicillin, cephalosporins, as well as chemotherapy drug nifuroksazid (erssefuril).
With the light forms of enteropathogenic escherichiosis, antibiotics are not advisable. In these cases, the treatment regimen includes:
- balanced diet;
- oral rehydration (maintenance therapy);
- enzyme preparations: abomin, festal, mikrazim, pancreatin (pancitrat, creon), etc .;
- symptomatic and bacterial preparations: acipol, bifystim, bifidumbacterin, lactobacterin, enterol, sporobacterin, biosporin, etc .;
- enterosorbents (filter-STI, smect, etc.).
If bowel dysfunction persists after 5-7 days of antibacterial therapy, the use of eubiotics in increased doses (bifido-, lactobacter, acipol, bifystim, etc.) for 1 intestinal flora (as with confirmed intestinal dysbacteriosis) is shown for 1 -2 weeks, enzymes and stimulating therapy. A good effect is applied within 2-3 weeks of combined prebiotic lactofiltrum, consisting of enterosorbent and ketosahar and stimulating the growth of its own microflora.