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Infectious disease

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Treatment of dyspepsia

Alexey Portnov, medical expert
Last reviewed: 20.11.2021

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The basis for treating dyspepsia and acute infections accompanied by dehydration is rehydration therapy. It is carried out in order to restore the water-electrolyte and acid-base state of the organism.

Rehydration is carried out by polyionic crystalloid solutions (trisol, chlosol, acesol). Colloidal solutions (gemodez, reopoliglyukin) can be used for the purpose of detoxification only in the absence of dehydration. Most patients with I-II degrees of dehydration use solutions of oral rehydration salts: citraglucosolane, glucosolan, regidron. Rehydration therapy is the basis for the treatment of acute infections accompanied by dehydration syndrome.

Rehydration therapy (intravenous and oral) is carried out in two stages.

Elimination of existing fluid losses. The volume of administered solutions as a percentage of body weight corresponds to the degree of dehydration, the rate of administration also depends on the degree of dehydration (from 30-40 ml / min at grade I to 120-130 ml / min at IV degree).
Correction of continuing fluid loss.

In addition to rehydration, the following groups of drugs are used to correct gastrointestinal disorders in infectious diseases.

Sorbents (polyphepan 1 tablespoon 3-4 times a day, polysorb, carbolong, etc.) in order to reduce intoxication.
Smecta (smectite dioctahedral) is a multi-purpose drug (sorbent and protector that protects the intestinal mucosa). Apply 3-4 packs (9-12 grams) per day.
Eubiotics (linex 2 capsules 3 times a day, bifidumbacterin forte, acipol, biosporin, etc.).
Enzyme preparations - oraza, abomin, pancreatin, etc. - 1 tablet (pills) 3 times a day with meals.
Metoclopramide - a blocker of dopamine receptors - to reduce vomiting and dyspeptic disorders apply 10 mg 1-3 times a day intramuscularly 1-2 days.
Spazmolitiki with pain syndrome: drotaverin to 0,04 g 3 times a day inside or 1 ml of 2% solution intramuscularly 1-2 times a day; papaverine; preparations krasavki (bellestezin, besalol).
Indomethacin is an inhibitor of prostaglandin biosynthesis, which contributes to the reduction of secretory diarrhea. Assign 50 mg 3 times at intervals of 3 hours for 1 or 2 days.
Octreotide is an inhibitor of the synthesis of active secretory agents, which contributes to a decrease in secretion and motor activity. Produced in ampoules of 0.05, 0.1 and 0.5 mg. Enter subcutaneously 1-2 times a day.
Calcium preparations that activate phosphodiesterase, which prevents the formation of cAMP. Recommended use of 0.5 g calcium gluconate per os 2 times with an interval of 12 hours.
Intestinal antiseptics effective against a wide range of gram-positive and gram-negative bacteria, dysentery amoebae and fungi of the genus Candida:
- intetriks 1-2 capsules 3 times a day;
- Enterol - antidiarrhoeal drug of biological origin (obtained from yeast Saccharomyces boulardii) is prescribed 1-2 capsules 2 times a day.
Antibiotics and fluoroquinolones are used to treat four intestinal infections: cholera, shigellosis, iersiniosis and campylobacteriosis.