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Treatment of Coxsackie and EVD infections
Last reviewed: 04.07.2025
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Most patients with Coxsackie and ECHO infections are treated at home. Only children with severe forms of the disease (serous meningitis, meningoencephalitis, neonatal encephalomyocarditis, myocarditis, uveitis) are subject to hospitalization.
Etiotropic treatment of Coxsackie and ECHO infections has not been developed. Treatment is limited to the prescription of symptomatic and pathogenetic agents. Bed rest is prescribed for the period of acute manifestations of the disease. Significant dietary restrictions are not necessary. In case of hyperthermia, an antipyretic is given, for headaches and muscle pain, paracetamol, ibuprofen, analgin, etc. are prescribed.
- In the development of serous meningitis or meningoencephalitis, dehydration is carried out:
- 20% glucose solution, 10% calcium gluconate solution are administered intravenously;
- a 25% solution of magnesium sulfate is administered intramuscularly (0.2 ml/kg for children under one year of age and 1 ml per 2 years of age for children over one year of age);
- Glycerol is prescribed at 1 teaspoon or dessert spoon 3 times a day orally.
Diuretics (lasix, mannitol) are indicated. A spinal puncture may also provide relief.
- In severe generalized forms in newborns, normal human immunoglobulin is administered intravenously at a rate of up to 1 g/kg per course, prednisolone at 3-5 mg/kg per day, rheopolyglucin, albumin, etc.
- Antibiotics are prescribed only in the case of a secondary bacterial infection and the development of pneumonia, otitis and other bacterial complications.
- In neonatal encephalomyocarditis, along with dehydration and anticonvulsant therapy, glucocorticoids (dexamethasone), pentoxifylline, nootropics (piracetam, nootropil), cardiac glycosides with ATP and cocarboxylase, antibiotics, etc. are used. A good therapeutic effect is achieved by using interferon inducers (cycloferon, children's anaferon, arbidol, etc.).
- In cases of acute heart failure, a 0.05% solution of strophanthin-K is administered intravenously in an age-appropriate dose per 20 ml of a 20% glucose solution or corglycon.