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Treatment of ascaridosis
Last reviewed: 06.07.2025
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In the acute stage of ascariasis, treatment is carried out with antihistamines. Calcium chloride, calcium gluconate, and ascorbic acid solutions are taken orally; in severe cases of the disease, parenteral administration is used. The larval stage of ascariasis is treated with a thiazolyl-benzimidazole derivative, mintezole (thiabendazole), at a dose of 25 mg/kg per day in 3 doses after meals for 5 days. Treatment of ascariasis can cause an increase in allergic reactions, so it must be carried out in a hospital against the background of desensitizing therapy up to the appointment of glucocorticoids in moderate doses for 5-7 days.
In the chronic stage, treatment is carried out with medamine, decaris, and pyrantel.
- Medamin, a derivative of carbamate-benzimidazole, is prescribed at a dose of 10 mg/kg in 3 doses after meals for 1 day. In case of massive invasion, treatment can be extended to 2-3 days.
- Decaris (levamisole), an imidazole derivative, is prescribed at a dose of 2.5 mg/kg per day in 2-3 doses after meals for 1 day.
- Treatment with pyrantel can be carried out in tablets; young children are given a suspension of the drug. Dosage regimen and frequency of administration by age:
- 1-2 years - 125 mg;
- 3-6 years - 250 mg;
- 7-12 years - 500 mg in 2 doses;
- 13-15 years old - 750 mg in 3 doses after meals for 1 day.
Children tolerate all three drugs quite satisfactorily. Treatment of children with massive invasion is best done in a hospital or day hospital.
Vermox (mebendazole) is highly effective against ascariasis, but the drug causes increased motor activity of helminths, which can lead to antiperistalsis, vomiting and roundworms entering the respiratory tract. In this regard, Vermox is not prescribed to children, especially in case of intensive invasion. In addition to specific drugs, multivitamins, enzyme preparations are prescribed, iron preparations in case of anemia, and a complete protein diet is provided. The effectiveness of treatment is monitored after 3 weeks by triple examination of feces.