Sweet Syndrome
Last reviewed: 23.04.2024
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[What causes the syndrome Sweet?
The cause of the disease is not known. Often observed concomitant malignant formation, especially hematological.
Sweet syndrome, not associated with malignancies, mainly affects women aged 30-50 years, the ratio of women and men is 3: 1 (men usually over 60-90 years). Disease syndrome Sweet can occur after the disease of the respiratory tract, gastrointestinal infection, use of drugs. Histopathological feature - edema of the upper parts of the dermis with a dense infiltrate of neutrophils. Vasculitis can develop.
How to recognize the syndrome of Sweet?
Patients develop fever, increase the number of neutrophils, and form dark red plaques and papules. Rarely there are bullous and pustular eruptions. Foci usually exist for days or weeks.
Sweet syndrome should be differentiated with erythema multiforme, acute red lupus erythema, centrifugal erythema, gangrenous pyoderma and erythema nodosum. Sometimes there is a combination of acute fever neutrophilic dermatosis and myeloprophylactic disease, and acute febrile neutrophilic dermatosis can occur in chronic myelocytic leukemia, acute myelocytic leukemia, Hodgkin's lymphoma, skin cell lymphoma, multiple myeloma.
How is Svith syndrome treated?
Treatment includes the use of systemic glucocorticoids, mainly prednisone 60 mg, orally 1 time per day for 3 weeks. It is also recommended the appointment of antipyretics. In severe cases, Sweet syndrome requires the administration of dapsone and potassium iodide.