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Staphylococcal infections: antibodies to Staphylococcus aureus in the serum
Last reviewed: 05.07.2025

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Staphylococcus is one of the most common microorganisms, in humans it mainly causes purulent diseases and complications in somatic and surgical diseases. The leading method of diagnosing diseases caused by staphylococcus is bacteriological. Serological diagnostics is aimed at identifying the titer of antibodies to staphylococci in the patient's blood serum.
Serological methods for diagnosing purulent-septic diseases include direct hemagglutination and ELISA. An increase in antibody titer after 7-10 days when examining paired sera is considered diagnostic. A single study has no diagnostic value, since almost 100% of adults have antibodies to staphylococci in their serum.
Determination of antibodies to staphylococci is used to diagnose purulent-septic processes caused by Staphylococcus aureus in the following diseases:
- inflammatory lung diseases;
- phlegmon, abscesses, furunculosis, tonsillitis;
- peritonitis, sepsis, pyelonephritis;
- staphylococcal food poisoning.
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