Rossolimo-Melkerson-Rosental syndrome
Last reviewed: 23.04.2024
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Rossolimo-Melkerson-Rosenthal syndrome is a chronically relapsing dermatosis of unclear etiology.
In its development, importance is attached to genetic factors, functional disorders of the nervous system such as angioneurosis, infectious and allergic mechanisms. It is manifested by a combination of granulomatous cheilitis (less infiltration and swelling of other parts of the face), paresis (or paralysis) of the facial nerve and folded tongue.
Pathomorphology of the Rossolimo-Melkerson-Rosenthal syndrome. In some cases, the picture is non-specific, tissue edema is observed, in others granulomatous changes are observed, identical with those in sarcoidosis or granulomatous cheilate of Misher, sometimes against a background of nonspecific lymphocytic infiltration, perivascular as well as peri-follicular granulomas are visible.
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