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Progressive rubella panencephalitis: causes, symptoms, diagnosis, treatment

Alexey Portnov, medical expert
Last reviewed: 23.04.2024

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Progressive rubella panencephalitis is a rare form of congenital rubella, which differs from the congenital rubella syndrome.

trusted-source [1], [2],

Epidemiology of progressive rubella panencephalitis

Progressive rubella panencephalitis - a rare pathology, manifests itself in the second decade of life.

trusted-source [3], [4], [5]

What causes progressive rubella panencephalitis?

Progressive rubella panencephalitis is caused by the rubella virus.

Pathogenesis of progressive rubella panencephalitis

The pathogenesis of progressive rubella panencephalitis has not been studied.

Symptoms of progressive rubella panencephalitis

Progressive rubella panencephalitis develops gradually. Characteristic of such symptoms are progressive rubella panencephalitis: cerebellar ataxia, spastic syndrome, epileptic seizures, progressive dementia. In the spinal cord, low pleocytosis, an increase in the protein content, mainly of the y-globulin. The course is progressive. The outlook is unfavorable.

Diagnosis of progressive rubella panencephalitis

Diagnosis of progressive rubella panencephalitis is the detection of high titers of IgM antibodies against rubella virus by the methods of RTGA, RIF, RSK in serum and cerebrospinal fluid.

trusted-source [6], [7], [8], [9], [10]

Differential diagnosis of progressive rubella panencephalitis

Differentiate progressive rubella panencephalitis with SSPE and other slow infections.

trusted-source [11]

What tests are needed?

General blood analysis

Analysis of cerebrospinal fluid

Rubella: antibodies of class IgM and IgG to the rubella virus in the blood

Treatment of progressive rubella panencephalitis

Treatment of progressive rubella panencephalitis is symptomatic.

How to prevent progressive rubella panencephalitis?

Progressive rubella panencephalitis can be prevented by vaccinating girls aged 8-9 years against rubella.

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