Medical expert of the article

Rheumatologist, immunologist

New publications

Ovarian antibodies in the blood

Alexey Portnov, medical expert
Last reviewed: 23.04.2024

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.

If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

Normally, there are no ovarian antibodies in the blood serum.

Ovarian antibodies (to ovarian cell antigen) were first detected in women with premature menopause, infertility and in vitro fertilization . This group of antibodies can include antibodies to Leidig cells, ovarian granulosa cells and placental syncytiotrophoblast. To determine antibodies to germ cells, the method of indirect immunofluorescence and ELISA (allows to determine the total antibodies and antibodies of different classes - IgM, IgG, IgA). These antibodies can be found in the blood of women many years before the development of clinical manifestations of premature ovarian failure.

In addition to ovarian antibodies, ELISA can detect antibodies to the transparent oocyst shell (zona pellucida), which are total and belonging to different classes of Ig (IgM, IgG, IgA), which have the same diagnostic value as ovarian antibodies.

trusted-source [1], [2], [3], [4], [5], [6]

Translation Disclaimer: For the convenience of users of the iLive portal this article has been translated into the current language, but has not yet been verified by a native speaker who has the necessary qualifications for this. In this regard, we warn you that the translation of this article may be incorrect, may contain lexical, syntactic and grammatical errors.