Treatment of osteoarthritis

Choosing a medication to treat osteoarthritis

Pharmacoeconomics is a science whose goal is the economic evaluation of the effectiveness of costs and results associated with the use of drugs. In Western European countries, it has been developing since the 60-70s of the 20th century.

Physical therapy for osteoarthritis

The treating physician must take into account that a decrease in the range of motion in one joint affects the biomechanics of adjacent distal and proximal joints.

Osteoarthritis: Education and social support

The treatment algorithm for patients with osteoarthrosis has its own characteristics. If for the vast majority of diseases, including non-rheumatic ones, the rehabilitation stage is preceded by outpatient or inpatient treatment, then for osteoarthrosis the algorithm looks different: rehabilitation - outpatient (less often - inpatient) treatment - rehabilitation.

Drug treatment for osteoarthritis

Treatment of osteoarthritis remains a serious problem, despite the fact that the list of drugs used has recently expanded significantly.

Modern treatment of osteoporosis

Currently, the prevention and treatment of osteoporosis are based on the use of two main groups of drugs: those that stimulate bone formation and those that inhibit bone resorption (antiresorptives).

Levels of osteoarthritis clinical trials

Preclinical studies examine the potential mechanism of action and therapeutic range (effective - toxic dose) of a drug.

Conducting clinical trials in osteoarthritis: ORS

The recommendations of the Osteoarthritis Research Society (ORS) are based on the division of anti-arthrosis drugs, proposed by WHO and ILAR, into two groups - symptomatic (fast- and slow-acting) and cartilage structure-modifying.

Conducting clinical trials in osteoarthritis: OMERACT III

Various rheumatology and non-rheumatology organizations (eg, EULAR, FDA, SADOA, ORS) have published guidelines for the design of osteoarthritis studies.

How do you prevent osteoporosis?

The strategy for prevention and treatment of osteoporosis is based on different approaches and “targets”. The overall goal of the strategy should be to reduce the incidence of fractures in the population or to improve the prognosis for those who have already suffered a fracture (population approach to prevention and treatment).

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