Medical expert of the article
New publications
Lesions of the larynx with multiforme exudative erythema: causes, symptoms, diagnosis, treatment
Last reviewed: 23.04.2024
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Multi-form exudative erythema of Gerbera is a rare itchy dermatosis, manifested by strongly itchy papules that rise above the surface of the skin, which is an acute cyclical disease characterized by a sudden symmetrical rash on the skin of the extensor surfaces of the extremities.
In some cases, dermatological manifestations are preceded by a prodromal period, manifested by general malaise, headache, chills, fever, sometimes joint pain. The disease usually begins in early childhood and, recurring, can continue until adulthood.
[Pathological anatomy of laryngeal lesion with multiforme exudative erythema
The rash consists of light-red and livid round, dense papules with a diameter of 0.3-1 cm. Within 3-4 days these eruptions increase, the central part of which falls and becomes cyanotic. When merging rashes formed a variety in shape and polycyclic development figures. In some cases, a new nodule forms in the center of the rash, forming the same concentric steepness as the first papule. In some cases, the mucous membrane of the lips, mouth, pharynx and larynx is affected.
Symptoms of laryngeal lesion with multiforme exudative erythema
The main subjective symptoms of multi-form exudative erythema are severe itching, which is objectively evidenced by pronounced scratching, often infected. Because of this, the primary rash soon transforms into a small foci of necrosis, often into a vesicle with serous contents, which is often suppressed. Over time, the skin is lichenized, the hair follicles atrophy, the axillary and inguinal lymph nodes increase. Eosinophilia often appears in the blood.
Bubbles on the oral mucosa and lip rims, inferior in size to the bubbles in pemphigus, quickly open, exposing the bleeding, dirty shade of erosion. The lips swell, the red border is covered with bloody and dirty crusts and cracks. Due to considerable soreness, eating is difficult.
Similar eruptions are observed in the larynx, in particular on the epiglottis, cherpalodnagortannye and vestibule folds, rarely on the mucous membrane of the ventricles of the larynx. These lesions disrupt the function of swallowing and, depending on localization, cause the appearance of dysphonia of varying degrees. The danger of laryngeal localization of multiforme exudative erythema is the possibility of secondary complications with pronounced edema and obstructive stenosis of the larynx.
A characteristic feature of multiforme exudative erythema is its relapse; there are patients who have a disease recurring once or twice a year, more often in the spring and autumn. Usually the first kurtosis or relapse lasts 2-3 weeks; common phenomena and fever, if they occur, last only a few days, but there are also severe cases with a longer duration. Isolated cases of multiforme exudative erythema of the larynx are not described.
Diagnosis of laryngeal lesions with multiforme exudative erythema
Diagnosis of special difficulties does not cause, as orofaringolaryngeal defeat is accompanied by a characteristic rash on the skin.
If skin manifestations are preceded by lesions of the mucous membrane of the upper respiratory tract, the diagnosis of multiforme exudative erythema of the larynx is difficult until the appearance of typical skin rashes. Differentiate the multiforme exudative erythema of the larynx follows from secondary syphilis, herpetic laryngitis, flat lichen, and others.
What do need to examine?
Treatment of laryngeal lesions with multiforme exudative erythema
Treatment of oropharyngeal and laryngeal manifestations of multiform exudative erythema reduces to the use of alkaline rinses, lubrication of rashes with 1% solution of methylene blue, inhalation of antibiotics in a mixture with hydrocortisone. To reduce pain apply powders with powder anestezina, applications 3-5% solution of cocaine, 3% solution of dicaine.
What prognosis are the lesions of the larynx with multiforme exudative erythema?
Lesions of the larynx with multiforme exudative erythema have always a favorable prognosis.