Symptoms of infectious mononucleosis in children
The disease in most cases begins acutely, with rising body temperature, nasal congestion, sore throat, swelling of the cervical lymph nodes, enlargement of the liver and spleen, in the blood there are atypical mononuclears.
Polyadenopathy is the most important symptom of infectious mononucleosis, the result of lymphoid tissue hyperplasia in response to generalization of the virus.
Very often (up to 85%) with infectious mononucleosis on the palatine and nasopharyngeal tonsils there are various overlapping in the form of islets and strips; they completely cover the palatine tonsils. Overlays of a whitish-yellowish or dirty-gray color, loose, bumpy, rough, easily removed, the tissue of the amygdala after removal of the plaque usually does not bleed.
In the blood, moderate leukocytosis is noted (up to 15-30 × 10 9 / L), the number of mononuclear elements of blood is increased, the ESR is moderately elevated (up to 20-30 mm / h).
The most characteristic sign of infectious mononucleosis is atypical mononuclear cells in the blood - elements of round or oval shape, ranging in size from an average lymphocyte to a large monocyte. Cell nuclei are spongy with nucleolus residues. The cytoplasm is wide, with a light belt around the nucleus and a significant basophilia to the periphery, and vacuoles are found in the cytoplasm. In connection with the peculiarities of the structure, atypical mononuclear cells have been called "broad-plasma lymphocytes" or "monolymphocytes".