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How is the plague prevented?
Last reviewed: 04.07.2025

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Non-specific plague prevention
- Epidemiological surveillance of natural plague foci.
- Reduction of rodent populations, pest control and disinfestation.
- Constant monitoring of the population at risk of infection.
- Preparation of medical institutions and medical personnel to work with plague patients, conducting informational and explanatory work among the population.
- Prevention of importation of the pathogen from other countries. The measures to be taken are set out in the International Health Regulations and the Regulations for the Sanitary Protection of the Territory.
Specific prevention of plague
Plague vaccination is a specific plague prevention, which consists of annual immunization with a live anti-plague vaccine of people living in epizootological foci or traveling there. People who come into contact with plague patients, their things, and animal carcasses are given emergency chemoprophylaxis.
Schemes for the use of antibacterial drugs in emergency plague prevention
Preparation |
Directions for use |
Single dose, g |
Frequency of use per day |
Duration of the course, days |
Ciprofloxacin |
Inside |
0.5 |
2 |
5 |
Ofloxacin |
Inside |
0.2 |
2 |
5 |
Pefloxacin |
Inside |
0.4 |
2 |
5 |
Doxycycline |
Inside |
0.2 |
1 |
7 |
Rifampicin |
Inside |
0.3 |
2 |
7 |
Rifampicin + ampicillin |
Inside |
0.3 - 1 0 |
1 - 2 |
7 |
Rifampicin ^ ciprofloxacin |
Inside |
03-0.25 |
1 |
5 |
Rifampicin + pefloxacin |
Inside |
0.3 + 0.4 |
1 |
5 |
Gentamicin |
V/m |
0.08 |
3 |
5 |
Amikacin |
V/m |
0.5 |
2 |
5 |
Streptomycin |
In,m |
0.5 |
2 |
5 |
Ceftriaxone |
V/m |
1 |
1 |
5 |
Cefotaxime |
V/m |
1 |
2 |
7 |
Ceftazidime |
V/m |
1 |
2 |
7 |
Rifampicin + ofloxacin |
Inside |
0.3-0.2 |
1 |
5 |