How is drug allergy treated?
Last reviewed: 23.04.2024
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In acute reactions, the treatment of drug allergies in children is to wash the stomach, salt laxative, the appointment of enterosorbents (activated carbon, polyphepan, etc.), antihistamines.
With multiforme exudative erythema, the patient is hospitalized, bed rest, copious drink, the above treatment is prescribed.
Treatment of drug allergy in children in the form of Stevens-Johnson syndrome consists in the appointment of glucocorticosteroids (in terms of 1-2 mg / kg prednisolone - a daily dose), infusion therapy - 5% glucose solution with isotonic sodium chloride solution. With complete parenteral nutrition, heparin is usually administered at a dose of 0.3-0.5 units per 1 ml of the transfused solution. Established a good effect of hemosorbtion, especially early conducted. When the bacterial infection is attached, antibiotics are prescribed.
Treatment of drug allergy in children in the form of Lyell's syndrome is the hospitalization of the child in the intensive care unit. Temperature protection mode. Prescribe parenteral prednisolone in a dose of at least 5-10 mg / kg per day, antihistamines also parenterally, infusion therapy, heparin at a dose of 10-15 units / kg per hour intravenously drip, broad-spectrum antibiotics active against staphylococci, diuretics , cardiac glycosides and (according to indications) other symptomatic therapy. The hemosorption is shown. Always sterile underwear. Sometimes the child is placed in a gnotobiological chamber.
Locally, when wet, apply 0.1-0.2% solution of potassium permanganate, 1% resorcinol solution, 2-5% tannin solution, 1-2% aqueous solutions of aniline paints, and then epithelizing ointments such as solcoseryl, etc. In case of mucous membrane damage - warm rinse with 10% solution of soda, local anesthetics. If the eyes are affected, ocular hydrocortisone ointment is poured 3-4 times a day.
If you do not spend on time treatment of drug allergies in children, the prognosis for this disease is serious, especially with severe manifestations of drug allergies, septic complications.
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