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Hapten immune thrombocytopenia.

 
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Last reviewed: 05.07.2025
 
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Haptenic immune thrombocytopenia is based on the formation of antibodies to platelet antigens that have been altered under the influence of viruses or microbes.

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Causes of Haptenic Immune Thrombocytopenia

The disease most often develops in preschool and primary school age after viral infections - acute respiratory viral infections, rubella, chickenpox, mumps, infectious mononucleosis or vaccination with a live measles vaccine.

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Symptoms of Haptenic Immune Thrombocytopenia

Symptoms of haptenic immune thrombocytopenia develop acutely. Formation of petechiae is spontaneous. Purpura manifests itself as petechial-spotted hemorrhages in the skin and subcutaneous tissue, bleeding from the mucous membranes, and nosebleeds. There may be gastrointestinal and uterine bleeding in girls at puberty. Hemorrhages do not tend to spread and do not create a blood depot under the skin. There are no specific and characteristic changes in the internal organs for this form of thrombocytopenic purpura. The maximum period of disappearance of clinical and hematological manifestations of the disease is 4-6 months, which is associated with the natural catabolism of antiplatelet antibodies. Spontaneous recovery is possible.

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Treatment of hapten immune thrombocytopenia

Treatment of hapten immune thrombocytopenia is carried out by prescribing the following drugs: dicynone, androxon, vitamin C. In case of severe thrombocytopenia and very pronounced hemorrhagic syndrome, prednisolone is prescribed for 3-5 days with rapid withdrawal (within 3-5 days).

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