Hapten immune thrombocytopenia

At the heart of haptenic immune thrombocytopenia is the formation of antibodies to the antigens of platelets, altered, under the influence of viruses or microbes.

[1], [2], [3], [4], [5], [6]

Causes of hapten immune thrombocytopenia

The disease often develops in pre-school and junior school age after the virus infections, including acute respiratory viral infections, rubella, chicken pox, mumps, infectious mononucleosis or vaccination with live measles vaccine.

[7], [8], [9]

Symptoms of hapten immune thrombocytopenia

Symptoms of hapthenic immune thrombocytopenia develop acute. The formation of petechiae is spontaneous in nature. Purple is manifested by petechial-spotted hemorrhage into the skin and underlying cellulose, hemorrhages from the mucous membranes, and nosebleeds. There may be gastrointestinal and uterine bleeding in girls at puberty. Hemorrhages are not prone to spread, do not create a blood depot under the skin. Specific and characteristic for this form of thrombocytopenic purpura changes from the internal organs there. The maximum period of disappearance of clinical and hematological manifestations of the disease is 4-6 months, which is due to the natural catabolism of antiplatelet antibodies. Perhaps spontaneous recovery.

Treatment of hapten immune thrombocytopenia

Treatment of haptenic immune thrombocytopenia is performed with the use of the following drugs: dicinone, androxone, vitamin C. In severe thrombocytopenia and very severe hemorrhagic syndrome, prednisolone is administered for 3-5 days with rapid cancellation (within 3-5 days).