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Eye damage in ichthyosis
Last reviewed: 23.04.2024
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Ichthyosis unites a group of disorders manifested by desquamation. In severe clinical course of ichthyosis, patients die due to the attachment of a common skin infection that can not be treated. The following forms of the disease are known:
- Ichthyosis vulgaris is an autosomal dominant disorder with no ophthalmic manifestations.
- X-linked form of ichthyosis - peeling of the scalp, face, neck, abdomen and extremities; thickening of the nerves of the cornea and discoid keratopathy. Surface opacities of the cornea may form, clouding of the posterior layers is less common.
- Lamellar and linear ichthyosis are severe forms of the disease with an autosomal recessive type of inheritance. Eye symptoms include ectropion and keratoconjunctivitis, usually of a secondary nature, due to the lack of an open eye.
- Epidermolysis hyperkeratosis and erythrokeratodermia are autosomal dominant disorders with involvement in the corneal pathological process.
Other syndromes characterized by ichthyosis include:
- Syndrome Sjögren-Larssen (Sjogren-Lars-sen);
- Netherton Syndrome (Netherton);
- The syndrome of Refsum;
- Spot chondrodysplasia;
- IBIDS syndrome;
- KIDS syndrome.
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