The life cycle of dysenteric amoeba begins when ingested in the gastrointestinal tract. Ways of infection with dysenteric amoeba fecal-oral, household. Together with the feces, cysts are released into the environment, over 300 million are released per day. They show great resistance to temperature changes and other adverse effects. So, cysts are able to remain for a month at a temperature of 20 ° C, a week in a moist and darkened environment, up to a week in chilled food, several months at minus values. They enter the person with dirty hands, unwashed products, contaminated water, by tactile contact with the hands of a sick person. Their carriers are flies and cockroaches. Factors associated with the development of pathology are pregnancy, protein deficiency, dysbacteriosis, worms - all that reduces immunity.
Cyst of dysentery amoeba
Cysts of dysenteric amoeba appear from the vegetative after the remission of the acute phase of the disease. Some of them turn into a luminary, others, appearing in a medium of condensed feces, become smaller, enveloped and encysted. They have 4 cores and are arranged in the same way as the nuclei of the vegetative form. Immature cysts can have from one to three cores. This is the most resilient form of dysenteric amoeba that can survive in an unfavorable environment and, once inside a person, resume the life cycle.
Invasive stage of dysentery amoeba
The invasive stage of the dysentery amoeba is characterized by an incubation period that lasts up to two weeks. At this time, the cysts move along the intestine. On the way of their progress, they are introduced into its mucous membrane. In this case, the transverse and descending parts of the large intestine are most vulnerable to injury. At this stage, moving, the cysts turn into a vegetative form that contains destructive enzymes for the intestinal walls - pepsin and trypsin. This helps the parasite to penetrate into its layers, down to the muscular ones, which becomes tangible to the person.
Tissue form of dysentery amoebae
The tissue form of the dysenteric amoeba is formed by the introduction of the luminal in the intestinal wall. Until now, scientists have not figured out the reason why this happens. But at this stage, amoeba damages the mucosa of the colon. It is this form of its existence that is found in patients with amoebiasis. Breeding, it provokes the formation of ulcers on the walls of the intestines, which lead to the accumulation of pus, blood, mucus. Conditions are created for the transformation of luminal and tissue forms into a larger vegetative form. They increase to 30 μm and are able to absorb red blood cells. Going outside, the vegetative form dies.