Rubella (Rubeola) - acute anthroponous infectious disease, transmitted by airborne droplets, manifested by moderate intoxication, fever, small-stalk rash, polyadenopathy and high risk of fetal damage in developing in pregnant women.
When complications develop, treatment of measles is carried out according to the principles of treatment of these diseases. With the development of pneumonia or otitis media, antibacterial therapy is prescribed in accordance with the results of sputum culture for sensitivity to antibiotics. With the development of encephalitis treatment is aimed at maintaining vital functions and fighting swelling-swelling of the brain.
In conditions of low incidence of measles diagnosis is complex and involves an assessment of the epidemic situation in the patient's environment, clinical observation in the dynamics and serological examination. A typical measles with spots of Filatov-Belsky-Koplik. Cough, runny nose, conjunctivitis and a rash that appears first on the head, can easily be diagnosed on the basis of a clinical picture.
The measles pathogen was first isolated by scientists D. Enders and T. Peebles from the body of a sick person in 1954. The measles virus is a shell single-stranded virus with a negative RNA genome, the genus Morbilivirus, the family Paramyxoviridae, which has a special affinity for mucopolysaccharides and glycoproteins, cellular receptors containing sialic acid.
Measles (morbilu) is an acute, highly contagious anthroponotic viral disease characterized by a cyclical course, manifested by general intoxication, maculopapular rash on the skin, pathognomonic rashes on the mucous membrane of the mouth. Catarrh of the upper respiratory tract and conjunctiva. The transmission path is airborne.
Human herpesvirus type 7 (HHV-7) is a member of the genus Roseolovirus, the subfamily Betaherpesvirtis. When electron microscopic examination, typical for herpesviruses were virions up to 170 nm in diameter. The virion contains an electronically dense cylindrical nucleus, a capsid, a tegument and an outer shell and has a significant morphological similarity to HHV-6.
Herpesvirus type 6 is considered the most likely etiologic agent of multiple sclerosis, neonatal fever with convulsive syndrome and infectious mononucleosis, Epstein-Barr virus-negative and cytomegalovirus, and HHV-6-associated encephalitis. HHV-6 is a cofactor of AIDS, some forms of carcinoma of the cervix and nasopharyngeal carcinomas.
Medicines, the effectiveness of which has been proven by controlled studies in the treatment and prevention of cytomegalovirus disease. Antiviral drugs ganciclovir, valganciclovir, sodium foscarnet, cidofovir. Interferon drugs and immunocorrectors in cytomegalovirus infection are not effective.
A study of the patient's blood for the presence of specific antibodies of class IgM and / or antibodies of IgG class is not enough to establish the fact of active replication of CMV. Nor to confirm the manifest form of the disease. The presence of anti-CMV IgG in the blood means only the fact of meeting with the virus. Antibodies IgG the newborn receives from the mother, and they do not serve as evidence of infection with cytomegalovirus. The quantitative content of IgG antibodies in the blood does not correlate with either the presence of the disease, nor with an active asymptomatic form of infection, nor with the risk of intrauterine infection of the child.
