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Disaccharidase-deficiency enteropathies - Treatment
Last reviewed: 04.07.2025

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Treatment of disaccharide-deficiency enteropathies. The main method of treating disaccharide-deficiency enteropathies, both congenital and acquired, is a diet with the exclusion or sharp limitation of the intolerant disaccharide. Thus, in case of lactase deficiency, milk and dairy products are excluded, except for calcined cottage cheese, which is usually well tolerated by patients. In the absence of a rapid and pronounced effect from the appropriate diet, enzyme preparations, astringents and carminatives are indicated.
Prevention of disaccharide-deficiency enteropathies consists of early detection of disaccharidase deficiency and timely prescription of a diet excluding intolerant sugars.
The prognosis is generally favorable. However, in cases of hereditary fermentopathy, with prolonged irritation of the small intestinal mucosa by fermentation products, structural changes may occur and chronic enteritis with malabsorption syndrome may develop.