The effects of vinegar poisoning

Vinegar, like any other substance, can be both beneficial and harmful to humans. The benefits of vinegar are undeniable: it is widely used in everyday life and cooking. Cooking and canning cannot be done without vinegar. It is also difficult to disagree with the statement about the harm of this substance: vinegar essence causes headaches, abuse leads to kidney damage and damage to the liver and stomach. When swallowing a large amount of vinegar essence or inhaling its vapors, vinegar poisoning may occur. This condition can be very severe and often ends in death.

Despite the apparent safety of vinegar essence, vinegar poisoning can be very dangerous, even fatal. It requires immediate assistance. First of all, it is important to neutralize the effect of the toxin, remove it from the body. Only after this can you move on to stabilizing the condition, normalizing the main indicators and restorative treatment.

The main danger of vinegar is that poisoning is accompanied by swelling, inflammation, and chemical burns. The severity of the pathological process is determined by the concentration and amount of the substance ingested. In many ways, the symptoms of intoxication depend on how the vinegar entered the body. When vinegar enters the mouth, a chemical burn develops first, after which the integrity of the mucous membrane is damaged, and severe damage to the digestive tract and stomach may develop. When ingested, significant disturbances in the blood occur.

Brain Damage from Vinegar Poisoning

Poisoning is often accompanied by damage to the brain, especially if first aid was not provided in a timely manner, and the poison penetrated from the gastrointestinal tract into the blood and then spread throughout the body.

The pathogenesis is based on a pathological change in the structure and function of the brain, which occurs under the influence of toxins that have directly penetrated the brain tissue with the blood flow. Also often the cause is a violation of cerebral circulation, or damage to the brain by autoimmune complexes that are formed in the body in response to the effects of poison, are highly toxic and aggressive, even in relation to internal tissues.

First of all, interneuronal connections in the cerebral cortex and subcortical structures are disrupted. Interneuronal connections and synapses are gradually destroyed, and neurons themselves are destroyed. The most dangerous is considered to be a violation of the hypothalamic-pituitary system, neuroendocrine regulation.

The reactivity of the cellular and tissue structures of the brain changes quite significantly, which is accompanied by the manifestation of excessive excitation or irritation, especially in the early stages of exposure to the toxin.

Usually, brain damage manifests itself suddenly. The main symptoms are fainting and sudden loss of consciousness, convulsions and burning pain. A person suffers from a feeling of compression, twisting of the muscles of the limbs, less often - the neck. Usually, a person loses consciousness or goes into a comatose state, which in the absence of adequate supportive therapy can last quite a long time.

If the brain damage is minor, the symptoms may increase gradually. Dizziness often occurs, which intensifies with sudden movements, changes in body position. Seizures and hallucinations gradually appear. Such symptoms may resemble alcohol intoxication. At first glance, it may seem that the person is drunk. Often, with the gradual progression of the disease, sleep disturbances occur, the person begins to delirium, weakness, chills appear, and the body temperature rises. Gradually, changes occur in the person's psyche.

First of all, behavior, coordination of movements, speech and sleep are disrupted. A person becomes emotionally overexcited, unrestrained, aggressive, can act in a state of affect, without controlling their actions.

[ 1 ], [ 2 ], [ 3 ]

Hemoglobinuric nephrosis in vinegar poisoning

This disease involves the deposition of hemoglobin in kidney cells. In this case, the renal tubules are affected. First of all, their functional state is disrupted. The main symptom that occurs in the early stages of the pathology is an increase in the body's sensitivity to the effects of various drugs and temperature factors. Pain may occur during urination, which is accompanied by impaired urine filtration and reabsorption processes.

The disease in most cases does not manifest itself immediately, while the damage occurs immediately after a large amount of vinegar essence enters the body. As a rule, a person begins to worry about chills, a fever occurs, which in most cases is characterized as an aseptic condition in which an infectious process does not develop, however, acute damage to the structure and function of the kidneys develops, and the inflammatory process develops and progresses.

A large amount of protein appears in the urine, and blood impurities may appear. This can lead to the formation of clots, casts that disrupt the lumen of the vessels, leading to the formation of thrombi. This contributes to damage to the epithelial cells first, then to a violation of tubular synthesis. A large number of free radicals are formed, intensive lipid peroxidation occurs, which negatively affects general metabolic processes and contributes to disruption and deterioration of the general condition of the body. The danger lies in the hemoglobin that enters the body. It can cause further disruption of kidney function.

Acute hemolysis, which triggers proliferative processes in the renal tubules, can be a consequence of vinegar intoxication. They primarily damage epithelial tissues and also lead to degenerative processes in the glomerular endothelium. Degenerative processes that develop in the tubular epithelium are a rather dangerous condition. The process can be accompanied by hemorrhage and interstitium, which is externally manifested as anemia, jaundice, and azotemia. According to histological signs, this disease has many similarities with necrotic processes in the kidneys. It is important to establish a differential diagnosis in order to exclude the possibility of developing necrotic processes, which can also occur with poisoning by poisons of any origin. Necrosis is usually accompanied by edema and exfoliation of epithelial cells. They tend to enter the lumen of the tubules, resulting in the exposure of the tubular basement membrane. There is an expansion of the proximal tubules, as well as a flattening of the epithelial tissues, resulting in the destruction of the brush border and an intensive release of hemosiderin.