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Classification of HIV infection / AIDS

Alexey Kryvenko, medical expert
Last reviewed: 04.07.2025

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Classification of HIV infection

WHO recommends distinguishing four stages of the disease:

initial (acute);
persistent generalized lymphadenopathy;
AIDS-associated complex as pre-AIDS;
full-blown AIDS.

In addition, recently it has been proposed to identify a 5th stage of the disease - AIDS dementia.

In Ukraine, the clinical classification of HIV infection by V.I. Pokrovsky (1989) has been adopted:

I. Incubation stage;
II. Stage of primary manifestations;
- A. Acute febrile phase,
- B. Asymptomatic phase,
- B. Persistent generalized lymphadenopathy.
III. Stage of secondary diseases:
- A. Weight loss of less than 10%, superficial fungal, viral, bacterial lesions of the skin and mucous membranes; herpes zoster; recurrent pharyngitis, sinusitis.
- B. Progressive weight loss of more than 10%; unexplained diarrhea or fever for more than 1 month; hairy leukoplakia; pulmonary tuberculosis; recurrent or persistent bacterial, fungal, viral, protozoal lesions of internal organs (without dissemination) or deep lesions of the skin and mucous membranes; recurrent or disseminated herpes zoster; localized Kaposi's sarcoma.
- B. Generalized bacterial, viral, fungal, protozoal and parasitic diseases; Pneumocystis pneumonia; esophageal candidiasis; atypical mycobacteriosis; extrapulmonary tuberculosis; cachexia; disseminated Kaposi's sarcoma; central nervous system lesions of various etiologies.
IV. Terminal stage.

In young children, the following stages of the disease are consistently identified:

subclinical;
lymphadenopathic;
localized opportunistic infections;
generalized opportunistic infections.

At the subclinical stage, clinical manifestations of HIV infection are completely absent.

ICD-10 code

820 A disease caused by the human immunodeficiency virus (HIV), manifested in the form of infectious and parasitic diseases.
820.0 HIV-associated disease with manifestations of mycobacterial infection (HIV-associated disease with manifestations of tuberculosis).
820.1 Disease caused by HIV with manifestations of other bacterial infections.
820.2 HIV-associated disease with manifestations of cytomegalovirus disease.
820.3 Disease caused by HIV, with manifestations of other viral infections.
820.4 HIV-associated disease with manifestations of candidiasis.
820.5 Disease caused by HIV, with manifestations of other mycoses.

820.6 HIV-associated disease with manifestations of Pneumocystis carinii pneumonia .
820.7 HIV-associated disease with manifestations of multiple infections.
820.8 Disease caused by HIV, with manifestations of other infectious and parasitic infections.
820.9 Disease caused by HIV, with manifestations of unspecified infectious and parasitic diseases.
821 A disease caused by the human immunodeficiency virus (HIV), manifested in the form of malignant neoplasms
821.0 HIV-associated disease with manifestations of Kaposi's lymphoma.
821.1 HIV-associated disease with features of Burkitt's lymphoma.
821.2 HIV-associated disease with features of other non-Hodgkin's lymphomas.
821.3 Disease caused by HIV, with manifestations of other malignant neoplasms of lymphatic, hematopoietic and related tissues.
821.7 HIV-associated disease with manifestations of multiple malignant neoplasms.
821.8 HIV-associated disease with manifestations of other malignant neoplasms.
821.9 HIV-associated disease with manifestations of unspecified malignant neoplasms.
822 Disease caused by human immunodeficiency virus (HIV), manifested as other specified diseases.
822.0 HIV-related disease with manifestations of encephalopathy (HIV-induced dementia).
822.1 HIV disease with manifestations of lymphatic interstitial pneumonitis.
822.2 HIV-associated disease with wasting syndrome manifestations.
822.7 HIV disease with manifestations of multiple diseases classified elsewhere.
823 Disease caused by human immunodeficiency virus (HIV) that manifests itself as other conditions.
823.0 Acute HIV infection syndrome.
823.1 HIV disease with manifestations of (persistent) generalized lymphadenopathy.
823.2 HIV disease with manifestations of hematological and immunological disorders, not elsewhere classified.
823.8 Disease caused by HIV, with manifestations of other specified conditions.
824 Human immunodeficiency virus (HIV) disease, unspecified.

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