Among the main diagnostic criteria are such symptoms as eosinophilia, bronchial asthma, as well as allergies in the anamnesis. In addition, eosinophilic pneumonia, neuropathy, inflammation of the paranasal sinuses, extravascular eosinophilia. If the patient has at least 4 of these diseases, the ESS can be diagnosed.
, , , , , , , 
The blood is taken for general analysis: for diagnosis of the disease, there should be an excess of the number of eosinophils 10% higher than normal, as well as acceleration of the process of erythrocyte sedimentation.
At the general or common research of urine there should be occurrence in it of the protein, and also increase in number of erythrocytes.
Transbronchial and cutaneous biopsy, as well as biopsy of subcutaneous tissue: in this case, pronounced infiltration of eosinophils in the walls of small vessels, as well as necrotizing granulomatous processes in the respiratory organs.
Immunological analysis to detect an increased number of ANCA antibodies. The focus here is on increasing the total IgE, as well as perinuclear antibodies that have antimyeloperoxidase activity.
, , , 
CT of the lungs - visualization of parenchymal accumulations is carried out in the process, mainly located along the periphery; It is also noticeable that the bronchial walls thickened, with expansion in some places, bronchiectasis is noticeable.
Microscopy of exudate located in the pleural fluid, as well as conduction of medical bronchoscopy to detect eosinophilia.
Carrying out ECHO-CG to detect symptoms of mitral regurgitation, as well as proliferation of connective tissue with the appearance of scars in the heart muscle.