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Arteriovenous fistula: causes, symptoms, diagnosis, treatment

 
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Last reviewed: 05.07.2025
 
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Arteriovenous fistula is an abnormal connection between an artery and a vein.

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Causes of arteriovenous fistula

An arteriovenous fistula may be congenital (usually in the area of small vessels) or acquired as a result of trauma (eg, a bullet or stab wound) or erosion of an arterial aneurysm into an adjacent vein.

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Symptoms of arteriovenous fistula

A fistula may cause symptoms of arterial insufficiency (eg, limb ulceration due to decreased arterial flow, embolism, or ischemia) or chronic venous insufficiency due to the effects of high arterial flow pressures on the injured veins (eg, peripheral edema, varicose veins, congestive pigmentation). If the fistula is superficial and palpable, the injured area is usually swollen and warmer than the rest of the skin, with distention and often pulsation of the superficial veins. A thrill may be palpated over the fistula, and auscultation may reveal a continuous purring murmur that increases in intensity during systole. Occasionally, high-output heart failure develops if a significant portion of the cardiac output is shunted through the fistula to the right side of the heart.

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Treatment of arteriovenous fistula

Congenital fistulas are not considered an indication for treatment unless serious complications develop (eg, lengthening of one leg in a growing child). If necessary, percutaneous endovascular treatments can be used with placement of occlusive structures to close the fistula. Treatment is rarely completely satisfactory, but complications can be controlled. Acquired fistulas usually have a single major connection, in which case surgical treatment is effective.

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