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Arteriovenous fistula: causes, symptoms, diagnosis, treatment
Last reviewed: 05.07.2025

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Symptoms of arteriovenous fistula
A fistula may cause symptoms of arterial insufficiency (eg, limb ulceration due to decreased arterial flow, embolism, or ischemia) or chronic venous insufficiency due to the effects of high arterial flow pressures on the injured veins (eg, peripheral edema, varicose veins, congestive pigmentation). If the fistula is superficial and palpable, the injured area is usually swollen and warmer than the rest of the skin, with distention and often pulsation of the superficial veins. A thrill may be palpated over the fistula, and auscultation may reveal a continuous purring murmur that increases in intensity during systole. Occasionally, high-output heart failure develops if a significant portion of the cardiac output is shunted through the fistula to the right side of the heart.
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Treatment of arteriovenous fistula
Congenital fistulas are not considered an indication for treatment unless serious complications develop (eg, lengthening of one leg in a growing child). If necessary, percutaneous endovascular treatments can be used with placement of occlusive structures to close the fistula. Treatment is rarely completely satisfactory, but complications can be controlled. Acquired fistulas usually have a single major connection, in which case surgical treatment is effective.