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Antibodies to hemophilic rod in serum
Last reviewed: 23.04.2024
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The Influenza rod ( Haemophilus influenzae ) infects only humans and is localized, primarily in the upper respiratory tract. Over the past 30-45 years, the incidence of systemic forms of infection caused by a bacillus of influenza type b, increased by 4 times, and more often began to recognize cases of lesions in adults. The allocation of the influenza rod in bacteriological cultures from the nasopharynx is not of diagnostic significance because of the wide spread of carrier sticks among healthy people (90%). To diagnose infection, examine blood, urine, pleural and joint fluid, cerebrospinal fluid, and others.
For serological diagnosis of diseases caused by stick influenza, agglutination and precipitation reactions are used. Determination of antibodies to hemophilic rod in serum is a retrospective method of diagnosing the disease, since it is necessary to examine serum in the first week of the disease and after 10-14 days. The increase in the titer of antibodies in 10-14 days is considered to be diagnostic by no less than 4 times when studying paired sera.
The definition of antibodies to the haemophilic rod is used to diagnose infections in the following diseases:
- chronic purulent inflammatory diseases of the lungs (bronchiectatic disease, lung abscess, pneumonia);
- meningitis;
- septic arthritis, cellulitis, epiglottitis.
The methods of RIA and EIA can be used to select patients for vaccination against the bacillus type B influenza and to assess its effectiveness.
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