Reference values of activated partial thromboplastin time (APTT)
Activated partial thromboplastin time (APTT) is one of the most valuable common tests to obtain an idea of the blood coagulation system. APTTV is a test that detects exclusively plasma defects of the internal X-factor activation system in phase I (formation of prothrombinase) of blood coagulation.
Determination of activated partial thromboplastin time - modification of the test for determining the recalcification time of stabilized blood (plasma). It has a higher sensitivity to deficiency of plasma clotting factors (except VII and XIII), however, when using this test, it is not possible to reveal the insufficiency of coagulation activity of platelets.
The elongation of activated partial thromboplastin time (APTT) reflects a deficiency of plasma factors (except VII and XIII) and is observed with their significant (below 25-10%) decrease. Elongation of activated partial thromboplastin time (APTT) indicates a predominance of hypocoagulation.
Reference values: 38-55 s. However, it should be noted that reference values in different laboratories may vary depending on the sensitivity and composition of the diagnostic kits.
Последнее обновление: 31.05.2018
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Medical expert editor
Portnov Alexey Alexandrovich
Education: Kiev National Medical University. A.A. Bogomolets, Specialty - "General Medicine"
The norm of the coagulogram is very important. The fact is that the analysis should correspond to some acceptable figures. Any deviation indicates the presence of problems in the human body. More details about this issue can be found below.
When fibrin fibers are cleaved, fragments are formed-D-dimers. When determining the content of D-dimers with the help of specific antisera, one can judge to what extent fibrinolysis, but not fibrogenolysis, is expressed in the test blood. The increased content of D-dimer is one of the main markers of activation of the hemostasis system, since it reflects both the formation of fibrin in the blood under study, and its lysis.
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