Acrodermatitis papular children (Gianotti-Crosty syndrome): causes, symptoms, diagnosis, treatment

Acrodermatitis of papular children (synovial syndrome of Gianotti-Crosti) is an acute disease, the development of which is associated with the hepatitis B virus, less often with other viral infections. It develops mainly in early childhood, but sometimes also in adults. Characterized by a symmetrical eruption of lenticular papules on the skin of the limbs, buttocks, face. Which is struck last. Their color is pink or red with a cyanotic shade, sometimes the rashes have a hemorrhagic appearance. There is usually no rash on the body, or it is very weakly expressed and has an erythema-squamous character. Unsharply expressed polyadenopathy is observed. Acute, usually anicteric variant of hepatitis. In the blood - a slight monocytic reaction. Skin rashes regress 1-2 months, and laboratory indicators that indicate a violation of liver function may exist for a longer time.

Pathomorphology acrodermatitis of papular children (Syndrome Dzhanotti-Krosti). In the epidermis a slight acanthosis with lengthening zidermalnyh outgrowths, focal intercellular edema, sometimes leading to the formation of vesicles, focal parakeratosis. In the dermis there is a massive swelling of the papillary layer. In its upper part, perivascular infiltration of a lymphostatocyte character with an admixture of zosinophils. Cells of infiltration often penetrate into edematous epidermis. Sometimes in these places, small extravasates of red blood cells are found.

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