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The causes of increase and decrease in phagocytic activity of neutrophils
Alexey Portnov, medical expert
Last reviewed: 19.10.2021
Last reviewed: 19.10.2021
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Diseases and conditions in which the phagocytic activity of neutrophils changes
Increase in the
- Antigenic irritation due to bacterial inflammation (prodromal period, period of acute infection) with normal activity of phagocytosis
- Leukocytosis
- Allergy
- Auto-allergic diseases
- Enhancement of antibody-dependent cytotoxicity and response to a donor graft
Decrease in the indicator
- Chronic inflammatory diseases of bacterial and viral nature
- Congenital defects of phagocytic system, Shedyak-Higashi syndrome, Down's syndrome, SLE, collagen diseases, diseases of immune complexes, lack of Ig, complement
- Treatment with cytostatics and immunosuppressants
- Ionizing radiation
- Secondary and primary immunodeficiencies
- Neoplasms
- Heavy burns, injuries, stress
- Intestinal and renal protein loss syndromes
- Malnutrition
- Insufficiency of phagocytosis
- Chronic inflammation