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Chronic duodenitis: causes
Last reviewed: 23.04.2024
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Depending on the etiology, it is common to isolate the primary and secondary chronic duodenitis. Primary chronic duodenitis is considered as an independent disease; secondary chronic duodenitis is a disease that accompanies or complicates various other diseases, primarily, diseases of the digestive system.
[Causes of primary chronic duodenitis
Primary chronic duodenitis is very rare. The main factors that cause it are irregular eating, frequent use of spicy, spicy, rough food, strong alcoholic beverages, excessive amounts of fats, carbohydrates; smoking; excessive passion for coffee, strong tea. The above factors stimulate the secretion of gastric juice, alcohol disrupts the motor-evacuation function of the stomach and duodenum. Smoking stimulates gastric secretion and inhibits the production of bicarbonates of pancreatic juice.
One of the reasons for the development of primary chronic duodenitis can be acute acute duodenitis. There is a definite hereditary predisposition to the development of primary chronic duodenitis.
It should be emphasized that the above reasons for the development of primary chronic duodenitis are not recognized by all researchers or are regarded as factors contributing to the development of this disease.
Most gastroenterologists believe that the most frequent direct cause of primary chronic duodenitis is a violation of the relationship between aggression and defense. Aggressive factors are hyperproduction of hydrochloric acid and pepsin, trauma of the mucosa of the duodenum; protective - the optimal state of cellular regeneration and circulation of the mucosa of the duodenum. However, it should be noted that the violation of the relationship between the factors of aggression and protection of the mucosa of the duodenum - this is probably not the etiology, but the pathogenesis of the primary chronic duodenitis. In recent years, the role of Helicobacter pylori in the development of primary chronic duodenitis has been discussed.
Causes of secondary chronic duodenitis
Secondary chronic duodenitis is much more common than the primary duodenitis. It can be a manifestation or complication of a number of diseases. The main causes of secondary chronic duodenitis are:
- Helicobacter pylori infection;
- duodenal ulcer;
- chronic gastritis;
- chronic pancreatitis;
- chronic hepatitis;
- chronic diseases of the alimentary tract;
- chronic enteritis, colitis;
- parasitic infestations;
- allergic diseases;
- diseases of the lungs and cardiovascular system, leading to tissue hypoxia;
- kidney disease with chronic renal failure.