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Treatment of exogenous allergic alveolitis
Last reviewed: 04.07.2025
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An elimination regimen (stopping contact with the allergen) is mandatory. In the acute phase, glucocorticoids are prescribed, for example, prednisolone up to 2 mg / kg per day orally. The dose should be reduced gradually from the onset of positive dynamics of the clinical picture (reduction of dyspnea, cough, normalization of FVD indicators). Then a maintenance dose of prednisolone 5 mg per day is prescribed for 2-3 months. Option of choice: pulse therapy with methylprednisolone 10-30 mg / kg (up to 1 g) 1-3 days, 1 time per month for 3-4 months. In the chronic stage of exogenous allergic alveolitis, a maintenance dose of prednisolone is prescribed for 6-8 months, sometimes longer.
It is also necessary to carry out breathing exercises and exercise therapy, symptomatic therapy (bronchodilators, mucolytics) if indicated. In some cases, plasmapheresis, hemosorption and immunosorption are used.
Prognosis of exogenous allergic alveolitis
The acute phase of exogenous allergic alveolitis has a favorable prognosis when contact with allergens is stopped and adequate treatment is given in a timely manner. When the disease becomes chronic, the prognosis becomes quite serious. Even after contact with the allergen has stopped, the disease continues to progress and is difficult to treat. The situation worsens with the development of pulmonary heart disease.