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Treatment of escherichiosis
Last reviewed: 06.07.2025
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Hospitalization of patients with escherichiosis is carried out according to clinical and epidemiological indications. Patients with moderate and severe cases of the disease are hospitalized in infectious disease hospitals. In mild cases, treatment of escherichiosis is carried out on an outpatient basis in the presence of favorable living, sanitary and hygienic conditions.
According to epidemiological indications, persons from decreed groups, patients from organized groups, as well as patients living in communal apartments and dormitories are subject to hospitalization.
Patients are hospitalized if there are people in the family who belong to the decreed groups.
In the acute period of the disease, patients are recommended gentle therapy (table No. 4, with normalization of stool - No. 2, during the recovery period - No. 13).
In mild cases of the disease, it is sufficient to prescribe oral rehydration therapy (regidron and other solutions, the amount of which should be 1.5 times greater than the loss of water with feces).
Enzymes (panzinorm-forte, mezim-forte), enterosorbents (polysorb, enterosgel, enterodesis for 1-3 days) are indicated. In mild cases of the disease, it is advisable to use intestinal antiseptics (intetriks, two capsules three times a day, neointestopan after each act of defecation, two tablets, up to 14 per day, enterol, two capsules twice a day) for 5-7 days. Mild and latent forms of escherichiosis do not require the administration of etiotropic drugs.
If the treatment of escherichiosis is carried out in a hospital setting, bed rest is indicated for the first 2-3 days. Etiotropic treatment of escherichiosis is prescribed. For this purpose, in moderate forms, one of the following drugs is used: co-trimoxazole, two tablets twice a day or fluoroquinolone drugs (ciprofloxacin 500 mg twice a day orally, pefloxacin 400 mg twice a day, ofloxacin 200 mg twice a day), the duration of therapy is 5-7 days.
In severe cases, fluoroquinolones are used together with 2nd-generation (cefuroxime 750 mg four times a day intravenously or intramuscularly; cefaclor 750 mg three times a day intramuscularly; ceftriaxone 1.0 g once a day intravenously) and 3rd-generation (cefoperazone 1.0 g twice a day intravenously or intramuscularly; ceftazidime 2.0 g twice a day intravenously or intramuscularly) cephalosporins.
In case of dehydration of II-III degree, rehydration therapy is prescribed intravenously with crystalloid solutions (chlorsol, acesol, etc.), which is carried out according to general rules.
In case of severe symptoms of intoxication, colloidal solutions (dextran, etc.) are used in a volume of 400-800 ml/day.
Antibacterial treatment of coliform escherichiosis with ongoing diarrhea should be combined with the use of eubiotics to correct dysbacteriosis (bifidumbacterin-forte, hilak-forte, etc.) for 7-10 days. Patients are discharged after complete clinical recovery, normalization of stool and body temperature, as well as a single bacteriological examination of feces, which is carried out no earlier than 2 days after the end of treatment.
Approximate periods of incapacity for work
In mild cases of the disease - 5-7 days, in moderate cases - 12-14 days, in severe cases - 3-4 weeks. There are no regulations for medical examination.