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Strongyloidiasis - Treatment and Prevention
Last reviewed: 04.07.2025
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Etiotropic treatment of strongyloidiasis is carried out with anthelmintic drugs. The drugs of choice are albendazole. carbendacim. An alternative drug is mebendazole.
- Albendazole is prescribed in a daily dose of 400-800 mg (for children over 2 years old, 10 mg/kg per day) in 1-2 doses for 3 days, in case of intensive invasion - up to 5 days.
- Carbendacim is recommended orally at a dose of 10 mg/kg per day for 3-5 days.
- Mebendazole is indicated orally after meals at 10 mg/kg per day in 3 doses for 3-5 days.
Antiparasitic treatment of strongyloidiasis is carried out against the background of taking antihistamines. The use of glucocorticoids is not recommended. Pathogenetic and symptomatic treatment of strongyloidiasis depends on the severity of the disease and disorders in the functioning of organs and systems.
With effective treatment of strongyloidiasis, a temporary increase (with a low initial level) or a significant decrease (with a high initial level) in blood eosinophilia is possible. Skin itching, exanthema, arthralgia disappear soon after treatment.
Monitoring of the effectiveness of treatment of patients with strongyloidiasis is carried out immediately after the end of treatment and after a month. For this purpose, feces are examined three times at intervals of 1-2 days for the presence of S. stercoralis larvae using appropriate methods. In doubtful cases, it is advisable to examine the duodenal contents.
For patients receiving immunosuppressive therapy, patients with HIV infection, even with negative control tests after effective treatment, it is advisable to carry out monthly prophylactic antiparasitic treatment of strongyloidiasis with the above-mentioned drugs in half doses in courses of 2 days.
Approximate periods of incapacity for work
The period of incapacity for work is determined individually for each patient.
Forecast
The prognosis is favorable in uncomplicated cases when etiotropic treatment of strongyloidiasis is carried out in the early stages of the disease. In severe cases, especially those occurring against the background of immunodeficiency, the prognosis is serious.
Clinical examination
Medical examinations are not regulated.
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Prevention of strongyloidiasis
Strongyloidiasis can be prevented by actively identifying patients among risk groups according to clinical indications: with gastrointestinal diseases (peptic ulcer), allergies (linear forms of urticaria). blood eosinophilia, as well as during preventive examinations. Measures to prevent infection, including professional infection. It is necessary to conduct systematic health education work among the population on individual prevention measures.