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Hematologist, oncohematologist

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Myelogram

Alexey Portnov, medical expert
Last reviewed: 19.11.2021

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Myelogram - the percentage of cell elements in smears prepared from the points of the red bone marrow. The bone marrow contains two groups of cells: cells of the reticular stroma (fibroblasts, osteoblasts, fat and endothelial cells), which constitute an absolute minority in number, and cells of the hematopoietic tissue (parenchyma).

Currently, red bone marrow biopsy is an obligatory method of diagnosis in hematology, since it allows to evaluate tissue relationships in the bone marrow.

Red bone marrow examination is conducted to confirm or establish the diagnosis of various forms of hemoblastosis and anemia. Myelogram should be evaluated, comparing it with the picture of peripheral blood. Diagnostic value is the study of bone marrow in the defeat of its lymphogranulomatosis, tuberculosis, Gaucher's disease, Niemann-Pick, metastasis of tumors, visceral leishmaniasis. This study is widely used in dynamics to evaluate the effectiveness of the therapy.

Reference parameters (norm) of myelogram

Elements of red bone marrow	Amount,%
Blasters	0.1-1.1
Myeloblasts	0.2-1.7
Neutrophils
Promyelocytes	1-4,1
Myelocytes	7-12.2
Metamyelocytes	8-15
Stabbed	12.8-23.7
Segmented	13.1-24.1
All neutrophilic elements	52.7-68.9
The neutrophil maturation index	0.5-0.9
Eosinophils (of all generations)	0.5-5.8
Basophils	0, -05
Lymphocytes	4.3-13.7
Monocytes	0.7-3.1
Plasma cells	0.1-1.8
Erythroblasts	0.2-1.1
Pronomocytes	0.1-1.2
Normocytes:
Basophilic	1.4-4.6
Polychromatophilic	8.9-16.9
Oxyphilic	0.8-5.6
All erythroid elements	14.5-26.5
Reticular cells	0.1-1.6
The erythrocaryocyte maturation index	0.7-0.9
Leucoerythroblastic ratio	2.1-4.5
The number of myelokaryocytes	41.6-195.0 × 10 ⁹ / L
Number of megakaryocytes	0.05-0.15 x 10 ⁹ / l or 0.2-0.4%

trusted-source [1], [2], [3], [4]

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