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Fusariums are causative agents of fusariosis

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Last reviewed: 06.07.2025
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Fusarium is caused by septate mold fungi of the genus Fusarium.

Fusaria - the causative agents of fusarium

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Morphology and physiology of fusarium

Fungi of the genus Fusarium form a well-developed mycelium of white, pink or red color. There are microconidia, macroconidia, rarely chlamydospores. Macroconidia are multicellular, spindle-sickle-shaped. Microconidia are oval, pear-shaped. They grow on Czapek medium in the form of fluffy colonies.

Pathogenesis and symptoms of fusarium

Fungi are widespread, especially on plants. In immunocompromised individuals, fungi can affect the skin, nails, cornea, and other tissues (F. moniliforme, F. sporotrichiella, F. anthapitum, F. chlantydosporum). Fever develops, rashes appear. The lesions are localized mainly on the extremities.

At low temperatures, the fungus F. sporotrichiella develops on cereals, producing mycotoxins. Eating such cereals that have overwintered under snow causes mycotoxicosis. Mycotoxicoses are also caused by eating grain products. The central nervous system is affected, with impaired coordination of movements.

Microbiological diagnostics of fusarium

Nails, skin, subcutaneous tissue, cornea, blood, the tip of a permanent catheter, vomit, feces, and tissue biopsies are examined. Fungi are isolated and their toxins are determined. RIF is used. Fluffy or cotton-like white colonies grow on nutrient media, which acquire a lilac-blue, pink-red, yellow, or green color as they age. Fungi form mycelium, micro- and macroconidia. Old cultures can form chlamydospores. PCR is sometimes used.

Treatment of fusarium

Fusarium is treated with amphotericin B, new triazoles (voriconazole or posaconazole).

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