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Diagnosis of staphylococcal infection
Last reviewed: 23.04.2024
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The diagnosis of staphylococcal infection is based on the results of a microbiological study, since the clinical manifestations are non-specific and do not allow in most cases to carry out differential diagnosis with similar clinical forms caused by another opportunistic pathogens.
The appropriate biosubstrates (pus, sputum, pleural exudate, blood, cerebrospinal fluid, urine, etc.) are used for the study. The isolated culture is examined for the presence of coagulase (coagulase test), the ability to enzymatically cleave mannitol, the ability to synthesize thermostable DNA-ase, agglutinate the sensitized erythrocytes of the sheep; the phage typing of the isolated strain is carried out. The rapid diagnosis of staphylococcal infection is based on the use of radar. It is necessary to determine the sensitivity of the isolated strain to antibacterial drugs (disc method or serial dilutions).
[Differential diagnosis of staphylococcal infection
Differential diagnosis of staphylococcal infection is based on the results of a microbiological study. The toxic shock syndrome is differentiated from septic and streptococcal toxic shock, scarlet fever, meningococcemia, rickettsial spotted fever, and leptospirosis. Measles, drug toxicosis.