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The causes of increase and decrease in immunoglobulin G
Last reviewed: 19.10.2021
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Reduction of the content of immunoglobulin G indicates a lack of humoral immunity.
Changes in the concentration of immunoglobulin G in the blood serum for various diseases
| Increase in concentration | Reduction in concentration |
|
Acute and chronic bacterial, fungal and parasitic infections Acute and chronic liver disease Cirrhosis of the liver, viral hepatitis Autoimmune diseases Rheumatoid arthritis Collagenoses, rheumatism Systemic lupus erythematosus Sarcoidosis, cystic fibrosis Waldenström's disease Myeloma disease Monoclonal Gammopathy Infectious mononucleosis Chronic lymphatic leukemia Reconvalence after bacterial infection Acute period of re-infection |
Physiological hypogammaglobulinemia (in children aged 3-5 months), congenital hypogammaglobulinemia or agammaglobulinemia Hemoglobinopathies Diseases that lead to the exhaustion of the immune system:
Treatment with cytostatics and immunosuppressants, ionizing radiation Chronic viral infection |