Medical expert of the article

Rheumatologist, immunologist

New publications

Antibodies to the adrenal glands in the blood

Alexey Portnov, medical expert
Last reviewed: 23.04.2024

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.

If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

Antibodies to the adrenal glands are directed against the microsomal structures of cells of the adrenal cortex. They belong to IgG, they possess organ-specificity and are more frequent in women. The determination of antibodies in serum is used to establish the pathogenetic mechanisms of the development of primary adrenal atrophy.

Antibodies are detected in 38-60% of patients with idiopathic Addison's disease. Over time, the concentration of antibodies in Addison's disease may change, and they may disappear. Antibodies to adrenal antigens can be detected in 7-18% of patients with tuberculous etiology of Addison's disease and 1% of elderly patients.

trusted-source [1], [2], [3], [4], [5], [6]

Translation Disclaimer: For the convenience of users of the iLive portal this article has been translated into the current language, but has not yet been verified by a native speaker who has the necessary qualifications for this. In this regard, we warn you that the translation of this article may be incorrect, may contain lexical, syntactic and grammatical errors.