Medical expert of the article
New publications
Preparations
Treatment with pumpkin seeds: indications, contraindications
Last reviewed: 03.07.2025

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Pumpkin seeds, like the pulp of this melon crop (Cucurbita pepo), contain a large number of useful substances, many of which have medicinal properties. Thus, raw pumpkin seeds ground with honey have long been used as an effective anthelmintic.
Indications pumpkin seeds
In our country, pumpkin seeds are officially classified as an anthelmintic, but today, when the biochemical composition of pumpkin seeds has been studied in more detail, the indications for the use of this natural product are not limited to helminthiasis, but include diseases of the cardiovascular system, intestines, liver, and prostate gland. Among the substances contained in these seeds, there are those that help with high cholesterol in the blood, VSD, low testosterone levels and decreased sexual function in men, etc.
However, doctors warn: despite all their potential medicinal properties, pumpkin seeds are an auxiliary remedy in the prescribed complex therapy.
Pharmacodynamics
The description on the pharmacy packaging states that pumpkin seeds have activity against helminths (tapeworms). Pharmacodynamics is provided by the carbonic amino acid cucurbitin, which, when the seeds are digested in the gastrointestinal tract, is converted by decarboxylation into substances that have a detrimental effect on intestinal parasitic worms.
Since pumpkin seeds do have a wider range of therapeutic effects, we should dwell on their composition in more detail. Pumpkin seeds contain antioxidant vitamin E in the form of alpha-, gamma- and delta-tocopherols; retinoids and carotenoids; niacin, choline, pantothenic and folic acids. So pumpkin seeds are recommended for use to reduce the level of oxidative stress that occurs in many pathologies.
Phenolic acids (hydroxybenzoic, hydroxycinnamic, coumaric, etc.) in the seeds help fight inflammation, allergies, decreased vascular tone and liver dysfunction.
Tetrahydrofuran lignans (pinoresinol, larisiresinol) have antioxidant and antimicrobial properties, and exhibit hormone-stimulating activity. Due to this, pumpkin seeds are useful for benign prostatic hyperplasia (enlarged prostate).
Polyunsaturated fatty acids (linoleic and alpha-linolenic) and omega-6 fatty acids strengthen the phospholipid membranes of cells and maintain the healthy condition of tissues of various organs.
Phytosterols (beta-sitosterol, desmosterol, campesterol, stigmasterol, spinasterol, d-stigmastenol, d7-avenasterol) help in reducing the level of low-density lipoprotein (LDL) cholesterol in the blood.
Pumpkin seeds also contain zinc, magnesium and potassium. Magnesium and potassium are necessary for the functioning of the myocardium and gastrointestinal tract, normal blood pressure and good condition of bone tissue. And zinc not only supports immunity, but also regulates cell growth and division, insulin secretion, skin condition, sleep, mood, and the level of male sex hormones.
Pumpkin seeds also contain amino acids, including tryptophan, leucine, and arginine. Sufficient tryptophan intake helps with sleep disorders, as it increases the synthesis of the pineal hormone melatonin. Leucine and arginine help restore tissue after inflammation, stabilize blood cholesterol levels, and increase testosterone levels in men.
Dosing and administration
For the treatment of helminthiasis in adult children, it is recommended to do cleansing enemas for two days (twice a day - in the morning and before bed) before using pumpkin seeds, and take a laxative at the end of the second day.
Peeled seeds (300 g) should be crushed and mixed with 4-5 tablespoons of water (you can add a teaspoon of honey). The mixture is taken on an empty stomach - one spoon at a time (over 60 minutes, with short intervals).
After three hours, a laxative is taken, and then (after 25-30 minutes) an enema is done.
For children, the dose of seeds is reduced depending on age: 75 g - at 3-4 years, 100 g - at 5-7 years, 150 g - from 8 to 10 years, 200 g - 11-14 years.
The method of using pumpkin seeds for the treatment of other diseases involves introducing them into the diet in an amount not exceeding 25-30 g per day (with plenty of liquid to prevent digestive problems).
Use pumpkin seeds during pregnancy
For medicinal purposes, use during pregnancy is not recommended.
Contraindications
Pumpkin seeds are not used in cases of increased stomach acidity, gastritis and gastric ulcer, spastic colitis, and low blood pressure.
Side effects pumpkin seeds
Interactions with other drugs
Storage conditions
Fresh, dry pumpkin seeds should be stored in the refrigerator in a tightly sealed container.
Shelf life
If storage rules are followed, the shelf life of pumpkin seeds is up to 6 months.
Attention!
To simplify the perception of information, this instruction for use of the drug "Treatment with pumpkin seeds: indications, contraindications" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.