Livarol during pregnancy

Liverol is designed to treat fungal diseases. Its active substance is ketoconazole, the medicinal property of which is based on the detrimental effect on the fats of fungal membranes and, as a result, inhibition of their development, and then death. Many women experienced uncomfortable symptoms of thrush, the causative agents of which are fungi of the genus Candida. This microorganism is in 80% of people, including the epithelium in the vagina. Own microflora is so balanced that it protects a woman from pathogenic microorganisms and does no harm to her. If the balance is disturbed, it begins to actively multiply, causing such a disease as candidiasis (folk thrush). The impetus for its development in pregnant women is a change in the hormonal background. Than to treat this category of women and whether it is possible to candles livarole at pregnancy?

Indications Livarola

Indications for the use of livarol is an acute and chronic form of candidiasis of the genital organs, the prevention of their mycoses due to the weakening of immunity after taking antibiotics. If thrush has appeared during pregnancy, treatment is mandatory, tk. It can lead to miscarriage or premature birth.

Release form

Liverol is available in the form of ointments, tablets and vaginal torpedo-shaped candles. The drug is very toxic, therefore candles are used to treat thrush during pregnancy (with certain reservations), since it is very toxic. Suppositories locally affect the causative agents of the disease, without harming the fetus. One candle contains 400 mg of the main substance. Its weight is 2.9-3.15 g, the color is from white to marble.

Pharmacodynamics

Pharmacodynamics of the drug is based on the antifungal action of the active substance ketoconazole, one of the many synthetic antimycotics of the second generation of topical application. Its mechanism is the violation of the production of ergosterol - the main "building material" of the cell membrane of fungi.

Pharmacokinetics

The pharmacokinetics of livarol is determined by the pharmacokinetics of ketoconazole, which refers to azoles, which are poorly absorbed when taken orally, and therefore are predominantly applied topically. When introduced into the vagina, livarol has a low resorption capacity and practically does not penetrate into the bloodstream.

Dosing and administration

How correctly to apply candles livarole at pregnancy? Suppository of lyvarol is administered once a day at night. To do this, you need to remove it from the package, lie on your back and insert it deeply into the vagina. The average duration of treatment is 3-5 days.

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Use Livarola during pregnancy

Despite the fact that the liver is not contraindicated to pregnant women for use, but its use is allowed only after the 12th week of pregnancy. Liverol is not prescribed for pregnancy in the first trimester. If, nevertheless, the doctor makes such a decision, then the benefit to the mother exceeds the potential risk to the fetus. Lovers of self-medication need to know about this. In the second trimester of pregnancy, the drug is used to treat candidiasis, and in the third - not only for treatment, but also for prevention.

Contraindications

Among the contraindications to the use of livarol is not only the first three months of bearing a child, but the child's age is up to 12 years and hypersensitivity to the components of the drug.

Side effects Livarola

Among the side effects noted irritation of the genitals: redness and swelling of the vaginal mucosa. There may also be frequent urination. There were cases of discharge after livery during pregnancy, pain during sexual intercourse. A sexual partner can also feel a burning sensation in the penis. Some women after using the drug faced with the appearance of discharge with an admixture of blood. Can I heal from lavarola during pregnancy? This is an excuse to show the doctor, but this is possible if the vessels are close.

Overdose

When following the rules of the regulations, there will be no overdose, especially since no more than a percent of the active substance enters the blood.

Interactions with other drugs

Interactions with other drugs are not due to the weak absorption of livarol. Simultaneous use with other vaginal antifungal agents weakens the effect of the latter.

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Storage conditions

Storage conditions provide places of room temperature distant from heat sources.

Shelf life

Shelf life is not more than two years.

Reviews

The experts' opinions are unambiguous: the drug is the leader in the treatment of candidal infection of the genital organs. The main arguments supporting this: affordable price, effectiveness, a small percentage of women with side effects as a result of treatment. Clinical trials confirmed: about 80% of patients were cured after 3 days of administering the lavarola suppositories, and after 5 days - up to 93%.

The majority of patients positively evaluated the treatment with lavarol. Rare negative comments belong to people who have had adverse reactions in the form of itching, swelling and inflammation of the vagina.

Analogues

Analogues of livarol are ketoconazole, dermazole, mikanisal, mycote, perchotal, sebosol, fungavis, mycosaral. They have different manufacturers and different costs, but the same active substance. In the absence of one drug in pharmacies, it can be replaced with another.

Livarol or pimafucin

Pimafucin is a polyene broad-spectrum antibiotic, its active substance is natamycin, the mechanism of action of which is different than that of ketoconazole. It binds to the sterols of the cell membrane of the microorganism, increasing permeability and destroying it. The drug is safe to use. Among the side effects are the same as that of the liver. In the treatment of thrush only vaginal suppositories are used, although the drug is also available in the form of tablets, ointments. Clinical studies show that the efficacy of pimafucine is slightly higher than that of lavarol, but the price is higher. You can resort to it at any time of pregnancy, unlike livarola. Duration of treatment from 3 to 6 days, the method of application is the same. In the responses of the patients there is a statement that pimafucin did not bring recovery and only, resorting to the livery, it was possible to get rid of thrush. In any case, liverar or pimafucin should be decided by the doctor. A pregnant woman should not be exposed to the risk of a future child and take medicines alone.

Terjinan or livarol

Terzhinan - another effective tool in the fight against vaginal infection. The clinical effectiveness of the drug is based on well-chosen components, complementing each other's action. It's an antiseptic, an antibiotic, and an antifungal drug. It is produced in tablets for vaginal use. For the safety of the future mother and fetus, treatment is performed topically with the use of vaginal suppositories. Before use, the tablet falls for half a minute in water, after insertion into the vagina in the lying position, it is not recommended to stand for 10-15 minutes. You need to do the procedure before bedtime once a day. The average duration of therapy is 10 days, but can be continued up to 20 days. In rare cases, local irritation may occur: burning and redness, in those prone to allergies - its manifestations. Comparing with lavarol, the advantages of the latter include a shorter period of treatment, the lack of a prednisolone - a hormone, a more convenient form in use. Terjinan or livarol - leave a choice to the doctor.