Calcium d3 nicomed in pregnancy

With the onset of pregnancy, the woman's body undergoes serious changes, both in hormonal terms and in the functioning of all systems. The musculoskeletal system is no exception, which is directly related to the intake of calcium into the body.

Calcium D3 Nycomed during pregnancy helps to cope with the deficiency of this important element, since with the appearance of the fetus the need for it increases several times.

The fetus needs calcium for growth and full development, and if its level is insufficient, all processes are slowed down and various disorders are possible. As a result, the baby may suffer from rickets, which develops against the background of calcium deficiency.

To suspect a microelement deficiency, it is enough to pay attention to the symptoms that indicate this. Among them are: drowsiness, convulsive states and pain syndrome in joints, muscles and bones. If any of the listed clinical manifestations appear, it is worth contacting a specialist.

Calcium D3 Nicomed belongs to a group of drugs that affect the digestive tract, and is also considered a mineral supplement. By following a certain dosage and recommendations for the duration of administration, a pregnant woman will be able to restore the necessary calcium composition in the body and provide it to the fetus.

Long-term use of this medicine requires regular monitoring of calcium and creatinine levels, which are reflected in a blood test. This is especially true for elderly people who are taking cardiac glycosides, diuretics (thiazide), and those with a tendency to form tartar.

The use of calcium d3 nicomed during pregnancy also requires monitoring to avoid the development of hypercalcemia and the appearance of clinical manifestations of renal dysfunction. In case of observation of such symptoms, it is necessary to reduce the dosage or completely stop taking calcium.

In order to avoid excess calcium intake, you need to strictly monitor the dosage of the drug, the duration of its use and your diet, especially those foods that contain a lot of calcium.

The use of calcium d3 nicomed during pregnancy is permitted only in certain months. Thus, in the first and second trimesters, additional calcium intake will help to replenish its deficiency in the pregnant woman's body. After all, this microelement is intensively used for the growth and development of the fetus, and with its deficiency, fetal skeletal development anomalies are possible.

However, the third trimester is characterized by an almost fully formed skeletal system, so excessive calcium intake can only strengthen the fetus's bone structures, which is undesirable before childbirth. Too strong fetal bones can damage the woman's birth canal and create difficulties during labor.

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Indications for the use of calcium d3 nicomed during pregnancy

Calcium is involved in a large number of reactions that make the human skeletal system a strong framework for organs.

Indications for the use of calcium D3 Nycomed during pregnancy include the treatment of a pathological condition that is accompanied by a deficiency of calcium and vitamin D3, as well as for preventive purposes.

In addition, indications for the use of calcium d3 nicomed during pregnancy include osteoporosis as an additional drug.

Calcium is considered a building material for the formation of strong teeth, bone structures and nail plates. In addition, this microelement is involved in the functioning of the brain and regulates hormonal levels.

During pregnancy, a larger amount of calcium is required than in a normal state, as a result of which, if the body is not replenished, a woman may experience a deficiency. It may manifest itself as toothache and tooth decay.

Bone fractures are also possible due to increased fragility and brittleness of bone structures. Of course, you can try to compensate for the lack of calcium with food, but you should remember that calcium is necessary for the development of the skeleton and teeth of the fetus, processes in which can suffer.

Release form

The drug is available in the form of chewable tablets. Their dosage is specially selected to comply with dosages and prevent the development of side effects. Thus, the form of release of the drug is presented in tablet form. Each tablet contains a third of the daily required amount of calcium and vitamin D3.

This form of release is very convenient, as it allows you to take a bottle with you and not miss taking the drug. One bottle can contain 20, 50, 100 tablets, the dosage of each is 500 mg of calcium and vitamin D3 - 200 IU.

Based on this, it is not difficult to understand that it is necessary to take up to 3 tablets daily. Although some experts still claim that during pregnancy it is enough to take 2 tablets - 1 in the morning and before bedtime.

It should also be taken into account that calcium can come from other sources, such as food or various vitamin complexes. Therefore, the amount consumed should be taken into account together with all sources of calcium.

There are two types of tablets, which differ in flavor additives. So, it is possible to choose the tablet you like - with orange or mint flavor.

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Pharmacodynamics

The role of calcium in the body is invaluable, therefore, for better absorption, it is recommended to use calcium D3, which takes part in the metabolic processes of phosphorus and calcium. In bone formations, destruction decreases and tissue density increases.

The pharmacodynamics of calcium d3 nicomed during pregnancy is based on the ability of this drug to promote mineralization of teeth in women. It is also worth noting that the drug helps to normalize the state of the nervous system of a pregnant woman, improving conductivity along nerve fibers, and participates in the work of the blood coagulation system.

From the nervous system side, calcium regulates the transmission of nerve impulses and their further conduction along nerve bundles, as a result of which the contractile ability of muscles is ensured. As for the hormonal system, calcium in combination with vitamin D3 prevents excessive secretion of the parathyroid hormone, which in turn activates the resorptive process in bone tissues, i.e. the leaching of the microelement from the bones.

Pharmacodynamics of calcium D3 Nycomed during pregnancy in combination with vitamin D3 ensures the correct formation of the fetus's skeleton, its cardiac and other muscles.

The medicine is a combination drug that restores the necessary level of calcium and vitamin D3, participates in their metabolism and in the formation and strengthening of teeth.

Pharmacokinetics

The main absorption processes occur in the small intestine. This concerns vitamin D3, as well as calcium of ionized structure, which enters the bloodstream due to active, vitamin-dependent transport.

The pharmacokinetics of calcium d3 nicomed during pregnancy is built due to the participation of the digestive tract, since most of the calcium is absorbed through the gastrointestinal tract. Approximately 99% of calcium accumulates in bone structures and teeth, the remaining amount of the microelement is located in the intra- and extracellular environment.

In the bloodstream, calcium exists in several states. Thus, half of the entire circulating volume is a natural active form of the ionized structure. About a tenth part moves with the blood flow in a complex with citrates, phosphate groups and other anions.

As for the rest of the calcium, which makes up about 40%, these are compounds with protein structures, mostly with albumins.

The pharmacokinetics of calcium d3 nicomed during pregnancy ensures its excretion through the kidneys with urine, intestines and pores of the skin through sweat.

Vitamin D3 is absorbed in the small intestine. Cholecalciferol and metabolites are in the bloodstream in the form of specific globulins. Cholecalciferol undergoes two stages of transformation: the first in the liver under the action of enzymes, and then in the kidneys to form 1,25-hydroxycholecalciferol.

It is this element that promotes the activation of calcium absorption. However, there is a part of vitamin D3 that is not subject to splitting. It is stored in muscle fibers and adipose tissue. The process of vitamin excretion is carried out by the kidneys and intestines.

Method of administration and dosage

Calcium D3 nicomed is approved for use during pregnancy, however, it is necessary to strictly take into account the dosages, in connection with this, the duration of the course and the dose should be selected by a specialist. Before this, the level of calcium in the body should be determined, since its excess can excessively strengthen the bones of the fetus, which will lead to complications during labor.

In addition to trauma to the birth canal, calcium deposits in the placenta are possible, which is also undesirable during pregnancy.

The method of application and doses are selected individually, since it is necessary to take into account the nutritional diet of the pregnant woman, because calcium comes with food. Thus, when consuming a large amount of dairy products, it is necessary to control the doses of the drug.

For each pregnant woman, the method of application and doses are different, but it is worth highlighting the maximum amount of microelement that can enter the body per day. Calcium should be at a level of less than 1500 mg, while for vitamin D3 the upper limit should not exceed 600 IU.

In addition, it is necessary to take into account that the microelement can be observed in breast milk, which is also not recommended when feeding a baby. The calcium dosage can change during the course, taking into account the duration of taking the drug, as well as the initial level of the microelement in the blood.

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Contraindications to the use of calcium d3 nicomed during pregnancy

One of the first contraindications should be the individual characteristics of the body, since intolerance to calcium or additional substances that are part of this drug can be transmitted genetically.

Such a reaction can manifest itself in local and general clinical symptoms, ranging from the appearance of a rash, swelling and redness of the skin, to nausea, vomiting and convulsions.

Contraindications to the use of calcium d3 nicomed during pregnancy also include the presence of phenylketonuria, hypervitaminosis D3 and urolithiasis with the formation of calcium stones. In addition, before starting to take the drug, it is necessary to examine the level of calcium in the blood, since an excess amount of the microelement also leads to various disorders in the body.

In addition, contraindications to the use of calcium d3 nicomed during pregnancy imply restrictions on the use of the drug by patients with renal failure in the subcompensation stage, in old age and in the immobilized position of the patient.

The use of calcium D3 Nycomed is not permitted in childhood, in cases of renal failure in the compensated stage and sarcoidosis.

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Side effects of calcium d3 nicomed during pregnancy

In most cases, side effects of calcium d3 nicomed during pregnancy when the rules for taking the drug are not followed. However, such reactions occur quite rarely and can be characterized by metabolic disorders, in particular, an increase in the level of calcium in the bloodstream and urine.

Side effects of calcium d3 nicomed during pregnancy are also possible due to improper functioning of the digestive tract. Thus, intestinal disorders, flatulence, abdominal pain and nausea are noted.

Only in some cases are skin manifestations observed. Among them, itching, swelling and rashes may occur. If such clinical manifestations occur, it is necessary to stop taking the calcium preparation and also control the consumption of foods that are rich in this microelement.

During the entire course of using the drug, it is necessary to determine the calcium level and, if its high level is detected, stop the therapeutic course. Excessive amounts of the microelement can harm not only the pregnant woman, but also the fetus.

Overdose

It is quite rare, but still possible to overdose on calcium if the rules for taking, duration and dosage of the drug are not followed. Conditions in which calcium levels increase can develop gradually or acutely.

Hypersensitivity to vitamin D3 is most pronounced, so it is necessary to carefully select the dosage, taking into account all the intake of vitamins and microelements into the body.

Overdose may manifest itself with such clinical symptoms as nausea, vomiting, intestinal upset, abdominal pain, muscle weakness, rapid onset of fatigue and even mental disorders.

In addition, in some cases, there may be an increase in appetite, an increase in the amount of urine excreted per day, the formation of calcium deposits in the kidneys, and disruptions in the conductivity and rhythm of the heart. With prolonged intake of calcium in large doses, damage to the urinary tract and accumulation of calcium in tissues may be observed.

If there is a suspicion of excessive calcium levels in a pregnant woman, thirst and vomiting may occur. In this case, it is necessary to examine the quantitative composition of the microelement in the blood and urine.

To reduce the symptoms of overdose, it is recommended to stop taking the drug, drink plenty of fluids to activate the excretion of calcium, and also monitor its intake from food.

In case of severe overdose, it may be necessary to use calcitonin, detoxifying solutions, diuretics (loop) and hormonal drugs.

Interactions with other drugs

Particular control over the dose and duration of calcium intake is necessary when taking this medicine in parallel with other drugs.

The decrease in the rate of calcium excretion is a consequence of the interaction of calcium d3 nicomed during pregnancy with other drugs, such as thiazide diuretics. When taking them together, the level of calcium in the bloodstream and urine of a woman should be regularly examined, since there is a high probability of developing hypercalcemia.

As for the interaction of calcium d3 nicomed during pregnancy with other drugs, for example, antibacterial agents, their accumulation is possible as a result of calcium disruption of absorption processes. Similar reactions concern quinolone antibacterial agents, tetracyclines and levothyroxine.

To avoid the development of adverse effects, they should be taken 2.5 hours or 5-6 hours after taking a dose of calcium.

In addition, calcium D3 nicomed can increase the therapeutic effect and toxic effects of cardiac glycosides when taken together. During the course, it is necessary to monitor the heart function using an ECG and the general condition of the pregnant woman.

When calcium is used simultaneously with bisphosphonates and calcium fluoride, the latter may not be fully absorbed, as a result of which they must be taken 1.5-2 hours before calcium.

Storage conditions

Each medicinal product requires certain conditions for its storage. They imply compliance with the temperature regime, humidity and expiration date specified in the instructions.

Storage conditions for calcium d3 nicomed during pregnancy include maintaining the temperature of the room in which the drug is located at a level not exceeding 25 degrees. In addition, direct sunlight should not be allowed to hit the packaging or the already opened drug.

In addition, the storage conditions of calcium d3 nicomed during pregnancy suggest storing it in a place where children have no access. When they consume large amounts of calcium, the clinical symptoms of overdose may appear. They are especially severe in children, since the drug is not approved for use in childhood.

Calcium tablets are stored in bottles of various sizes. Thus, the package may contain 20, 50 or 100 tablets. This bottle has an outer cardboard package, preventing the impact of negative factors directly on the drug.

Best before date

The instructions for calcium D3 nicomed reflect the expiration date and conditions necessary to preserve the medicinal properties of the drug during the specified period.

The expiration date is the date of manufacture and final use. After this period, and for calcium D3 nicomed it is 3 years, the use of the drug is prohibited.

Throughout the expiration date, the drug has the therapeutic properties indicated in the instructions and confirmed by research by the pharmaceutical company.

Once this period ends, the drug can harm the body, especially pregnant women. In addition, during the expiration date, it is necessary to adhere to certain rules for storing calcium.

It is not recommended to store the tablet form of calcium outside the bottle, as in this case it will be exposed to environmental factors.

Calcium D3 Nicomed during pregnancy is necessary to restore the necessary level of calcium in the body. However, you should be careful, since its excessive intake can have an undesirable effect. During the course of taking the drug, it is necessary to take into account the intake of calcium with food.