With the fact that the erythromycin ointment contains a strong antibiotic, there is also the presence of certain nuances in its application, which relate to the interaction of this drug with other drugs.
In addition to the incompatibility with some antibiotics of the group of lincosamides ("Lincomycin" and "Klindomycin"), erythromycin ointment for acne is an antagonist of the antimicrobial drug "Chloramphenicol", often used in the treatment of eye infections, as well as its analogues, the most famous of which is "Levomycetin". These drugs have exactly the opposite effect, and therefore their joint application will only reduce the effectiveness of treatment.
Antibiotics of beta-lactam (penicillin, cephalosporin and carbapenem series) when combined with erythrocyline in different forms lose their effectiveness as bactericidal preparations.
Erythromycin is able to enhance the toxic effects of certain drugs, creating an increased concentration in blood plasma. Such drugs include "Theophylline", "Aminophylline", "Cyclosporine", as well as caffeine and some medicines, the decay of which occurs in the liver.
Hormonal contraceptives under the influence of erythromycin begin to cope worse with their duties, and this must also be taken into account when using erythromycin ointment that is able to penetrate deeply into tissues and body fluids.
When using erythromycin ointment as a remedy for pimples and acne, it must be remembered that pre-cleaning the skin with face and body scrubs containing abrasive particles and having an exfoliating effect can lead to excessive irritation and drying of the skin.
In any case, before you start using erythromycin ointment as a remedy, you should consult your doctor about the safety of its use, especially if you are shown taking other medications.