Vitamins with hyaluronic acid

Vitamins with hyaluronic acid refer to vitamin-mineral complexes or biologically active additives (dietary supplements). Different manufacturers produce different in composition means, combining hyaluronic acid with vitamins A, C, E, macro elements and substances of plant origin.

The names of vitamins with hyaluronic acid, such as biocomplex Vitamins with hyaluronic acid, Doppelherz Beauty-Lifting complex with hyaluronic acid (Queisser Pharma, Germany), vitamins with hyaluronic acid Lora (RF), Solgar hyaluronic acid (USA), KWC Hyaluronic Acid (Japan), Premhyal capsules (hyaluronic acid and selenium), etc.

It should be noted that in some pharmacological classifications, preparations containing hyaluronic acid (Acidum hyaluronicum) or, more often, the sodium salt of hyaluronic acid-sodium hyaluronate (as well as sulfates of chondroitin and glucosamine) are referred to the group of bone and cartilage tissue metabolism correctors. These drugs can be injected into the joints (and this is the only way they are used in the West) or taken orally. But containing hyaluronic acid vitamins - it's unquestionably dietary supplements, at best - orthomolecular means.

Indications for the use of vitamins with hyaluronic acid

Complexes of hyaluronic acid + vitamins are recommended to be used as an auxiliary for improving metabolism - with age-related skin problems (dryness, loss of turgor, wrinkles), articular inflammatory diseases and cartilage degeneration (arthrosis, coxarthrosis, osteochondrosis) ophthalmologic pathologies (dry keratoconjunctivitis, destructive processes in the vitreous of the eye and damage to the cornea).

They are also offered to be used for preventive purposes - in the surgical treatment of diseases in ophthalmology and after cosmetic plastic surgery. However, there is no evidence of the effectiveness of the use of vitamins with hyaluronic acid, as this requires clinical trials, which are not performed in the production of dietary supplements.

Contraindications to the use of vitamins with hyaluronic acid include the age of up to 15 years, individual hypersensitivity or intolerance of substances in their composition (in particular allergies), elevated or decreased platelet levels in the blood, and severe renal dysfunction.

The use of vitamins with hyaluronic acid during pregnancy and during lactation is contraindicated.

The main form of production of these vitamin supplements is tablets or capsules.

Pharmacodynamics

To date, with respect to biologically active additives, there is no requirement to explain the specific mechanisms of action of their components on the biochemical processes in the body, therefore, in the description of vitamins with hyaluronic acid, general information is given most often, occasionally for each substance that is included in their composition.

First of all, this is hyaluronic acid itself, which is contained in most cells of the body. But in particularly high concentrations, it performs the most important anatomical function in the structure of the extracellular elastin-collagen matrix of the basal layer of the epidermis, in the connective tissues, the synovial fluid of the joint cavity and the vitreous body of the eyes. Hyaluronic acid is an acidic glycosaminoglycan (mucopolysaccharide) - a negatively charged heteropolysaccharide, that is, a carbohydrate polymer. Its spiral molecule consists of a repeating sequence of two disaccharides (D-glucuronic acid and DN-acetylglucosamine) and has a large molecular weight (in the range of 1 to 1.5 million Da). Due to the presence of hydrophilic carboxyl groups, hyaluronic acid is able to bind water molecules in the collagen matrix in a ratio of 1: 1000.

But the statements of some manufacturers that "hyaluronic acid activates fibroblasts and stimulates the synthesis of collagen" from the point of view of biochemistry is not explained in any way. In addition, no manufacturer of vitamin BADs indicates which kind of hyaluronic acid it is used: low molecular weight animal origin or synthesized sodium hyaluronate whose molecule size is too large to be absorbed by the endothelial cells of the gastrointestinal tract.

Pharmacokinetics

How the components of dietary supplements in the body are transformed and how they are derived from it, that is, the pharmacokinetics of vitamins with hyaluronic acid, is not studied: this is also not required in the production of food additives.

It is known that endogenous hyaluronic acid in the tissues of the body breaks down approximately in 72 hours, and in the epidermis - per day. Therefore, the process of its synthesis is continuous, but with age, unfortunately, slows down.

What happens with hyaluronic acid ingested with a tablet or capsule of dietary supplements, manufacturers describe something like this: "Hyaluronic acid, contained in the preparation, stimulates the synthesis of collagen and elastin."

Nevertheless, if hyaluronic acid is a complex carbohydrate, then in the gastrointestinal tract - by the action of saliva, gastric juice and intestinal enzymes-glucosidases - it must be split up to disaccharides, and this will have to turn into monosaccharides and their derivatives. But hyaluronic acid is a heteropolysaccharide and, when bound to cell proteins, enters complex biochemical complexes. Split endogenous hyaluronic acid into disaccharides (glucuronic acid and acetylglucosamine) is only capable of the enzyme hyaluronidase.

But the enzyme of saliva lysozyme can cope with hyaluronic acid, included in the dietary supplements. But we will repeat: biochemical studies of the metabolism of components of bioadditives companies-producers either do not, or do not advertise their results ...

Doppelherz with hyaluronic acid

Doppelherz Beauty The lifting complex with hyaluronic acid or vitamins Doppelherz with hyaluronic acid, according to the manufacturer, contain 100 mg of hyaluronic acid in each capsule. Also in this bioadditive are:

• biotin or vitamin B7 - 150 mg (triple daily dose); with its lack, there are various problems with the skin, as well as muscle aches and depressive conditions.
• 6 mg of vitamin B5 (pantothenic acid) covers 120% of the daily human needs. This vitamin is recommended for use with progressive alopecia, joint pain and cramps, as well as in cases of impaired vision and memory.
• lipophilic antioxidant tocopherol (vitamin E) - 20 mg, which is twice the daily physiological rate of its entry into the body. Vitamin E is able to increase the formation of hemoglobin, collagen and muscle proteins, and also does not oxidize vitamin A and unsaturated fatty acids. Half of the ingested tocopherol is first introduced into the lymph (absorbed into the stomach), and then into the systemic circulation, by binding to plasma proteins.
• beta-carotene (isomer of vitamin A), is involved in the synthesis of proteins and acid mucopolysaccharides.
• vitamin C, is particularly active in tissue metabolism and collagen synthesis.

BAD vitamins Doppelherz with hyaluronic acid also contains microelements: zinc (for better recovery of tissue cells) and selenium, which has antioxidant properties and stimulates metabolism.

Dosing and Administration: one capsule per day, during the meal. Duration of admission is 30 days, repeated use is possible one month after the end of the first course.

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Biocomplex with hyaluronic acid

Judging by the accompanying instructions, a biocomplex Vitamins with hyaluronic acid can help against scars and with adhesions after operations, and also help restore lost skin tone. And this should ensure that it contains glycosaminoglycans with hyaluronic acid content, collagen powder, salmon milk extract, pig's placenta powder, vitamin C, elastin peptide (from tuna), sucrose and fatty acid ester.

As a comment, we note that the sodium (or calcium) salt of deoxyribonucleic acid, derived from milk from salmonids, "is absorbed by the body and stimulates the working capacity." Collagenol (collagen powder) contains protein, polysaccharides and premixes of vitamins C and E. The lipophilic fraction of the tissues of the placenta of pigs (very popular in the Far East) is rich in biologically active ingredients, including trace elements and vitamins.

Elastin peptides from bones and tuna skin are composed of alpha-amino acids and refer to peptide biogenic regulators, which are supposed to stimulate cellular metabolism. Aether sucrose and fatty acids - it's just a food gel-like emulsifier E473.

The way of application and dose of this supplements: within a month 2-3 tablets per day (during meals).

Vitamin Solgar

Complex vitamins with hyaluronic acid Solgar - Hyaluronic acid 120 mg (Solgar Vitamin & Herb, USA) - contains hydrolyzed collagen, chondroitin sulfate and vitamin C and is recommended as an adjuvant for pathologies of joints (soreness and stiffness) and age-related dermatological and cosmetic problems.

Hyaluronic acid and vitamin C have already been discussed, but the following should be known about chondroitin. Chondroitin sulfate is a part of cartilage and intraarticular fluid, it is directly related to the synthesis of cartilage tissues, tendons and ligaments, and also promotes the formation of collagen and the synthesis of hyaluronic acid. Moreover, chondroitin sulfate can reduce the activity of lysosomal hyaluronidase, an enzyme that cleaves hyaluronic acid.

We advise you to carefully read the instructions to the dietary supplements: they should use only chondroitin sulfate with a low molecular weight (from the cartilage of salmonids) so that when ingested it can be adsorbed into the digestive tract and then "embedded" into the affected tissues of the human cartilage.

Vitamin Solgar with hyaluronic acid is taken with meals - one tablet a day.

Laura's Vitamins

Anti-aging vitamins with hyaluronic acid Laura contain (in addition to hyaluronic acid), vitamins (C and E), as well as the alkaloid of the perennial grassy dioscorea liana (yamsa) - diaskorin.

This plant alkaloid promotes the activation of the endogenous synthesis of the steroid hormone dehydroepiandrosterone (DHEA) by the adrenal glands. In turn, DHEA stimulates the production of androgens, estrogens and at least one and a half dozen important hormones, including polypeptide growth hormone somatotropin (STH). Somatotropin increases the synthesis of muscle protein, bone and connective tissues, as well as collagen and chondroitin.

Since the level of DHEA after 30-35 years begins to gradually decrease, the stimulation of its production (and incidentally, the synthesis of somatropin in the pituitary gland) positively affects the condition of the skin. But it should be borne in mind that an excess of STH can lead to the development of diabetes and functional disorders of the thyroid (hypothyroidism).

This dietary supplement is recommended for a month - one tablet a day (during meals).

Reviews about vitamins with hyaluronic acid

For the most part, feedback on vitamins with hyaluronic acid is negative, although there are also positive comments based on personal experience of their use. Of course, do not forget that there are no drugs that help absolutely everyone without exception. And BADov it concerns first of all.

And it is necessary to remember that hyaluronic acid is the main component of healthy skin, and about half of its amount in the body is contained in the matrix of the dermis. In a study conducted in Otsuma Women's University (Japan), 96 women aged 22 to 65 years took vitamins with hyaluronic acid from a Japanese company - three capsules per day for one and a half months. At the end of the study, 80 women reported that their skin became more hydrated and smooth, and even traces of acne erupted.