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Terginan in pregnancy

, medical expert
Last reviewed: 03.07.2025
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Terzhinan during pregnancy is practically one of the most frequently used in obstetric practice and approved drugs today. A pregnant mother is characterized by the presence of immunodeficiency. Susceptibility to infection with various infectious diseases is high. Moreover, many of them may already be in the mother's body, but not manifest themselves until the moment of weakness with health. Some problems are associated with the vaginal microflora, this can be both candidiasis and gardnerellosis. It is important to detect these problems in time and begin to actively fight them.

Indications for the use of Terzhinan during pregnancy

The drug is used to treat many diseases. Naturally, all of them are associated with vaginal microflora. Thus, it can be used for non-specific recurrent vaginitis. This condition is characterized by a constant change in the "composition" of the microflora. Simply put, it indicates the presence of an inflammatory process. Even an infection that has entered the bladder can be to blame for this. The drug actively fights bacterial vaginosis, as well as vaginitis of trichomonas etiology.

The medicine copes well with vaginitis of mixed etiology. Especially if the problem was caused by anaerobic flora, as well as the presence of yeast-like fungi. The drug can be used to prevent purulent-inflammatory complications before surgical interventions in the pelvic area. The spectrum of action of the drug is really wide. Its effectiveness has been repeatedly confirmed. Most importantly, it is absolutely safe.

Release form

Terzhinan is produced exclusively in the form of vaginal tablets. One such suppository contains enough useful components that can have a positive effect on the woman's body and relieve her of inflammatory processes. Thus, one suppository contains 200 mg of ternidazole. This is the main component. The auxiliary substances are neomycin sulfate in the amount of 100 mg and prednisolone sodium metasulfobenzoate 3 mg. But that's not all, it also contains excipinite. It contains geranium and clove oil. These components have an anti-inflammatory effect.

One package contains 6 or 10 suppositories, depending on the manufacturer. When purchasing Terzhinan during pregnancy, you need to start from your own needs. Usually, the duration of treatment is 7-10 days. Therefore, preference is given to packaging number 10.

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Pharmacodynamics

Terzhinan is a combination drug for local use. It is widely used to eliminate gynecological problems. It has an active antibacterial, antifungal and anti-inflammatory effect. It contains powerful components that help to achieve a positive effect.

Ternidazole. This is an antifungal drug that belongs to the group of imidazole derivatives. Neomycin sulfate is a broad-spectrum antibiotic. It belongs to the group of aminoglycosides. Nystatin is also an antibiotic, but an antifungal one. It belongs to the group of polyenes. Prednisolone is a dihydrogenated analogue of hydrocortisone. All these components together have an incredible effect on the body and help cope with many problems. Each component is responsible for its own function, thereby allowing you to displace viruses and infections.

Pharmacokinetics

Ternidazole. This is an antifungal drug that belongs to the group of imidazole derivatives. It is capable of inhibiting the synthesis of enzymes of the cell membrane component. All this leads to the accumulation of the active component inside the wall of the fungi, thereby disrupting its structure and leading to complete destruction.

Neomycite sulfate helps in this action. It has a bactericidal effect on gram-positive microorganisms. Its mechanism of action is to influence ribosomes, as well as active inhibition of cell protein synthesis. Resistance to microorganisms develops slowly.

Nystatin is highly active against yeast-like fungi. It is able to bind to the cell membrane of the fungus and thereby disrupt its permeability. Thus, the growth of negative cells slows down. As for Prednisolone, it in turn suppresses the functions of leukocytes. Thus, it limits their migration to the affected area. In addition, the substance is able to inhibit the activity of phospholipase A2. Which ultimately leads to the suppression of the synthesis of prostaglandins and leukotrienes.

Method of administration and dosage

The tablet is used at night by inserting it deep into the vagina. One suppository per day is enough. The product should be inserted before bedtime. This is convenient from the point of view that the woman will not move actively and thus allow the tablet to be absorbed. After insertion, it is recommended to lie down for 10-15 minutes without moving. The duration of treatment with Terzhinan during pregnancy is 10 days.

If the expectant mother suffers from candidal vaginitis, the therapy can be increased to 20 days. If menstruation has begun (such cases occur during pregnancy), it is necessary to continue therapy with the drug. Before the moment of administration, the product should be kept in water for literally 30 seconds, so that it is thoroughly moistened.

There are no special recommendations regarding use. It is enough to simply follow the instructions. An individual treatment plan can be prescribed by a doctor, in which case it is worth following his recommendations.

Use of Terzhinan in the 1st trimester of pregnancy

The product can be used even in the first trimester of pregnancy. Despite the fact that it contains antibiotics, it is not capable of having a negative effect on the developing fetus. The fact is that the tablet does not pass anywhere beyond the vagina. It is not absorbed into the blood and does not penetrate the body in any way. Therefore, there are no contraindications. If a woman has fetal development pathologies or individual characteristics, it is worth consulting a doctor. In any case, it is not recommended to use Terzhinan on your own during pregnancy.

The first trimester has always been the most dangerous. During this period, it is recommended to refuse any means. But it is also impossible to leave the inflammatory process unattended. Because infection of the uterus can lead to infection of the fetus. Ultimately, termination of pregnancy is not excluded. Therefore, treatment should be carried out with caution.

Use of Terzhinan in the 2nd trimester of pregnancy

The second trimester of pregnancy is not as dangerous as the first and third. There are no special restrictions regarding the use of certain drugs. Naturally, antibiotics are prohibited. Despite their content in Terzhinan, it is actively used. The fact is that this drug is absolutely safe for both the mother and the child. It does not penetrate the body at all, so it is not able to be absorbed into the blood and even more so to get into the mother's milk.

The dosage during this period is no different from the standard treatment regimen. If a woman experiences discomfort, the dosage can be prescribed individually or the treatment period can be significantly reduced. When using any medication, it is necessary to consider the positive effect for the mother with the possible negative impact on the baby's body.

Naturally, it is not worth leaving the problem untouched either. It can give a lot of negative complications, including infection of the baby and the risk of termination of pregnancy.

Use of Terzhinan in the 3rd trimester of pregnancy

In the third trimester, you always need to be especially careful. The fact is that as you approach the moment of birth, you should not give your body additional stress. This applies not only to taking medications, but also physical and emotional overstrain.

In general, suppositories of this type can be used at any stage of pregnancy. However, special caution should be exercised for the first time and in the last months. Antibiotics and other serious medications are not recommended. Despite its rich content, including a group of antibiotics, Terzhinan is used even in the last months of pregnancy. It is not capable of harming the body of the mother and child. Therefore, concerns here are unnecessary. But, despite this, it is highly recommended not to use the drug on your own. You should always adhere to an individual use scheme and seek help from a doctor in case of discomfort.

Terzhinan suppositories during pregnancy

Sometimes the joyful moments of future motherhood can be overshadowed by visits to the doctor. This not only spoils the mood, but can also harm the body. Thus, a young mother is exposed to the negative influence of many microorganisms, bacteria and infections. Her body is in a state of stress. Therefore, any harmful "residents" can penetrate the body and cause inflammatory processes in it.

Most often, problems of the genital area bother, namely candidiasis, vaginitis and vaginosis. In this case, treatment should be immediate, because there is a risk of infection of the child not only during the pregnancy itself, but also during childbirth. It is known that thrush can harm the baby's vision.

In order to eliminate unpleasant diseases, it is enough to resort to the help of Terzhinan suppositories. Yes, they contain antibiotics, but they do not harm the baby. The suppository does not go anywhere beyond the vagina and is not even absorbed by the blood. Therefore, there should be no worries. The medicine is prescribed to absolutely everyone. Exceptions are those girls who suffer from hypersensitivity to some components of the drug. The product is absolutely safe for both the mother and the child. Despite this, it should be used only according to special recommendations.

Is it possible to take Terzhinan during pregnancy?

The main aspect of treatment with the drug is its use in the form of suppositories. This is a combined remedy that has a lot of positive properties. Thus, it has an antifungal effect, and also acts as an antibacterial antibiotic and acts as an antiseptic. That is why this drug is in special demand.

This product is available in the form of tablets for vaginal use. The action of the drug is based on its rich composition. Yes, it contains an antibiotic, but due to its non-toxicity, Terzhinan can be used even during pregnancy. Perhaps, this is its main feature. In addition, the drug is widely used during breastfeeding. But this does not mean that it can be used indiscriminately. Everything is done according to clear indications of a specialist. Today, this product is one of the few that, having such a rich composition, does not harm the baby at all.

Contraindications for use

In general, Terzhinan has no contraindications during pregnancy. Because its effect does not go beyond the vaginal mucosa. All components included in its composition are not absorbed into the blood and do not penetrate the body. Therefore, it simply cannot negatively affect the fetus.

Despite this, there are contraindications. The fact is that women may have a banal allergy to the components included in the drug. The product is rich in antibiotics, although their dosage is negligible. But this may be enough to develop a persistent allergic reaction. Therefore, people with hypersensitivity should refuse it.

If a woman does not suffer from allergic reactions, she can safely use the medicine. True, after consulting a specialist. Because it is simply necessary to take into account the individual characteristics of each organism.

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Side effects

In some cases, after the drug is administered, a woman may feel discomfort. This includes a slight burning sensation or irritation. In this case, it is advisable to consult a specialist and stop taking the suppositories. Most likely, the woman has too sensitive a mucous membrane or an allergic reaction to any component of the drug. It is not worth the risk, it is necessary to learn everything in detail about this condition.

Side effects of Terzhinan during pregnancy usually manifest themselves in the form of local reactions and do not go beyond them. You can feel discomfort already for the first minutes after inserting the suppository. After a while, nothing appears. This can be caused by both an allergic reaction and incorrect insertion of the suppository itself. Some women suffer from increased vaginal vulnerability. If the pain decreases over time, you should not stop treatment. Usually, the inflammatory process subsides after several uses of the drug.

Yellow discharge after terzhinan during pregnancy

Many women start to be frightened by the appearance of discharge. It is worth understanding why they appear. So, in most cases, they do not pose any danger. The fact is that the suppository has some features. When inserted into the vagina, it begins to dissolve. The mucous membrane seems to absorb the necessary components. But it does not need everything. Therefore, the remains of the suppository can gradually come out during the next day after insertion. This is a completely normal process. It is observed both when using vaginal suppositories and rectal suppositories.

The principle of operation of suppositories is the same. The mucous membrane absorbs the necessary components, everything else flows out safely. Therefore, many women are advised to use daily pads during the period of using suppositories. There are no other reasons for which yellow discharge may be observed. If there are some doubts, it is still worth consulting a gynecologist.

Overdose

There have been no cases of overdose. The fact is that the drug is not able to be absorbed into the blood, so its increased concentration in the body is simply impossible. If a woman takes the drug in an increased dosage, then the maximum that will happen is that the general condition will worsen. It is possible to eliminate all symptoms, as well as worsen the manifestations of the disease. In this case, you need to remove the suppositories from the vagina and seek help from a specialist.

An overdose is possible if the drug has entered the body. For unknown reasons, a woman could simply swallow the medicine. In this case, you need to immediately wash out the stomach. After all, the components of terzhinan can cause severe poisoning and harm the baby. Because immediately after oral administration, the drug can penetrate the placenta to the child. You should not even try to cope with the problem on your own. You need to wash out and wait for the ambulance. The treatment is symptomatic.

Interactions with other drugs

No interactions between Terzhinan and other medications have been identified. Despite this, it is not worth using the drug together with other medications. After all, we are talking about a pregnant girl. In this case, it is generally recommended to refuse any medications. Combining them on your own is even more impossible.

In some cases, with a more advanced form of thrush and other inflammatory processes, several drugs are prescribed at the same time. Such a decision can only be made by the attending physician who is monitoring the woman's pregnancy. After all, despite the complete safety of some drugs, they should still be used with caution. In any case, even a small risk of harm always remains. The body of each pregnant girl is so individual that you can expect anything.

In no case should you make a diagnosis by comparing your own symptoms with the same signs described on the site or heard from a friend. A gynecologist should make a diagnosis and prescribe treatment.

Storage conditions

Usually, candles are stored in the refrigerator. The fact is that due to their composition and streamlined shell, they can melt quickly. Therefore, keeping them at room temperature will lead to spoilage. Naturally, you should not expose them to direct sunlight. As the instructions say, terzhinan can be stored at a temperature of 25 degrees. but still, the refrigerator is the optimal condition. Before use, the tablet is cut off, wait 5-10 minutes and as soon as it warms up, you can use it.

If there are already children in the house, it is better to hide the drug away. After all, to the touch it may remind the baby of candy, and even the unpleasant smell will not scare him. Therefore, to avoid poisoning, it is worth finding the optimal place for storage. This can be a dark place, without direct sunlight and an acceptable temperature. Such conditions will preserve the shelf life of the drug. If the packaging is damaged or opened, it is not recommended to use the suppositories.

Best before date

Terzhinan has a shelf life of 3 years. During this period, it must be stored under certain conditions. It is recommended to place the candles in the refrigerator, even though the optimal storage temperature may be 25 degrees Celsius. It is still advisable to put them in the refrigerator. This will prevent them from melting and spoiling.

After the expiration date, the use of the product is prohibited. Especially for a pregnant mother. Do not feel sorry for the medicine, it is better to get rid of it. Throughout the entire shelf life, pay attention to the appearance of the packaging. There should be no visible damage or punctures. Otherwise, Terzhinan cannot be used during pregnancy. Most likely, it has lost its main pharmacological properties and will not bring any benefit.

Compliance with storage conditions is a guarantee of a long service life of the preparation. If the product has melted, it should also be thrown away. It is not recommended to freeze it or use it.

Analogues

When choosing a quality treatment, many mothers pay attention not only to the effectiveness of the drug, but also to its safety. Today, there are many medications that can help in the fight against inflammatory processes. Thus, both Terzhinan and Pimafucin are widely used. Because of this, many mothers wonder which is better and which of these should be used.

Much has been said about the beneficial properties of Terzhinan. It is completely safe, does not harm the mother and child. In addition, it is effective and its only contraindication is hypersensitivity to its main components. But what can be said about Pimafucil.

Many mothers praise Pimafucin. Indeed, the drug is able to relieve inflammatory processes. Moreover, most often 6 days are enough to completely cure. In some cases, relief comes after 10 days. But it does not always help. The drug has a weaker composition and therefore it is not always easy for it to fight the infection, especially if the woman has had it for a long time. Therefore, the undisputed leader is Trezhinan, and side effects of this drug occur much less often.

Terzhinan or Polygynax during pregnancy?

Terzhinan contains neomycin, an antibiotic that can fight many bacteria and infections. Nystatin and Prednisolone help it with this. Thanks to their combined activity, the effect is simply amazing. Most importantly, the drug can be used even during pregnancy. The chances of harming the baby are negligible. If you follow all the recommendations, the treatment will be not only effective, but also safe. The main feature of the drug is the removal of unpleasant symptoms in a short period of time. It is enough to use one suppository to feel significant relief. It is important to complete the treatment and not stop, even if the discomfort is gone. After all, there is always a risk of chronicity.

As for Polygynax, everything is a little different. Yes, the product also fights inflammatory processes and destroys all unfavorable microorganisms. But it is stronger, so there is a risk of harm to the baby. It contains three antibiotics. Unlike Terzhinan, Polygynax is not able to remove several infections at the same time. For example, if they have different forms of formation. Therefore, eliminating only bacteriological inflammation, there is a risk of aggravating the course of an infectious disease. In this matter, Terzhinan is most effective. Therefore, preference is most often given to it.

Macmiror or Terzhinan during pregnancy?

There are no special differences between these drugs. For example, they contain nystatin, which helps fight many types of infections and bacteria. Some gynecologists believe that Macmiror is much safer than Terzhinan. Perhaps this is true. But Terzhinan is not particularly toxic and is not capable of harming a developing organism. It is difficult to say for sure which is better.

Macmirror has the same indications as Terzhinan. It actively fights thrush, and also eliminates inflammatory processes that were caused by the presence of fungi, bacteria and trichomonads. It cannot be used in case of hypersensitivity to some of its components. The composition of the drug includes Nifuratel and Nystatin. In combination, they can expand the antimicrobial effect. The components of the drug are not absorbed through the blood and do not penetrate the body. They are used for 7-10 days. The principle of use is the same as Terzhinan. Which of these drugs to choose is decided by the attending physician. Most often, preference is given to Terzhinan, due to its effectiveness.

Reviews

According to most doctors, the safest and most effective medicine for combating genital tract diseases in pregnant women is Terzhinan. It is prescribed in almost 95% of cases. This is due to the fact that the drug is not capable of causing harm to the developing organism.

There are both positive and negative reviews regarding the use of Terzhinan. Naturally, good descriptions prevail. The fact is that this remedy, despite containing antibiotics in its composition, is able not only to help a woman cope with the problem, but also to protect her baby. Terzhinan does not cause side effects and can be used in any trimester of pregnancy.

Despite all its positive aspects, there are also negative reviews. It is simply impossible without it. Each woman's body is individual, especially during pregnancy. Therefore, even the slightest sensitivity to some components of the drug can lead to side effects. Naturally, this will negatively affect the opinion of the product. Some women have too delicate vaginal mucosa, so the use of any drugs leads to discomfort.

You should never base your choice on reviews alone. You need to consult a doctor and choose an effective treatment based on your body's characteristics.

Attention!

To simplify the perception of information, this instruction for use of the drug "Terginan in pregnancy" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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