The time during which a small man grows and develops in the womb of a woman is a period when a woman also needs to be extra careful when taking various medications. After all, even those drugs that are considered relatively safe in pregnancy (for example, the same "Ibuprofen"), in some situations can cause irreparable harm.
When they talk about the safety of Ibuprofen during pregnancy, they basically mean the 2nd trimester, when the risk of miscarriage or premature birth is relatively small. This is the safest period when the basic vital systems of the fetus are formed, so taking medications less often causes disruptions in the development of the child.
It should be noted that there was no toxic or teratogenic effect on the fetus for Ibuprofen. Studies say that taking the drug is not capable of causing fetal death in the womb or causing mutations that will subsequently cause disability. But scientists do not exclude that the drug, with regular use, can provoke non-severe disorders, such as anomalies in the structure of the heart or abdominal wall in a child.
Experts do not have a common opinion about the possibility of using "Ibuprofen" during early pregnancy. In small amounts, it is considered harmless to the fetus and any developmental disorders of the child can be expected only after prolonged use, so doctors do not prohibit taking the drug at this time, but only ask to limit its reception as much as possible. For example, take 1 tablet of NSAIDs only at high temperatures and pains that can not be managed by safe alternative means.
But limiting the use of "Ibuprofen" during pregnancy in the first trimester is not only related to this. There is a suspicion that taking the drug may become a risk factor for involuntary miscarriage. True, the statistics of such cases are based primarily on miscarriages that occurred almost immediately after conception during the first couple of weeks. Therefore, doctors treat her with doubt, suspecting that such failures could provoke a drug taken before conception on the eve of ovulation. The changes he made in the endometrium of the uterus could cause rejection of the organ of a fertilized egg. They also could cause a violation of the formation of the tissues of the amniotic egg (placenta), as a result of which they were unable to retain the fetus.
However, there is a danger in the 1st trimester of pregnancy, and it can not be ignored. Less dangerous during this period is "Paracetamol", which can be taken with headache and toothache, as well as to reduce the temperature. True, with severe pain in the teeth and gums, it is unlikely to cope. It's not for nothing that doctors strongly advise you to treat your teeth before the pregnancy, and not only because the carious cavities are the source of infection for mom and her unborn baby, but also because the possibilities for treating moderate and severe pain in pregnancy are limited.
Danger "Ibuprofen" represents and in the last 3 months of pregnancy. He, although not an antispasmodic, is able to inhibit the process of contracting the walls of the uterus, which significantly complicates the birth process. When the time of childbirth arrives in the woman's body, the production of estrogens increases, which increase the sensitivity of the receptors in the uterus to acetylcholine. It is acetylcholine that causes the reduction of the walls of the uterus during childbirth, which allows the fetus to move in a generic way. It is believed that ibuprofen is able to block hormones necessary for the stimulation of labor, therefore it is not recommended to use it after 30 weeks of pregnancy.
Another unpleasant feature was noticed behind the drug. In the prenatal period, the pulmonary artery of the fetus is connected to the arch of the aorta by means of the arterial duct, which ends with an orifice in the atrial septum. Thus, the venous blood of the fetus can mix with the arterial blood, which is a necessity during the time of finding the baby in the womb, where it can not breathe with the help of the lungs and thus get the body's oxygen. Blood thanks to him goes around the lungs.
After the birth of the child, when the baby begins to breathe on his own, the need for a duct, which, after the name of his discoverer, was named Botallov, disappears. Usually, the hole through which the venous and arterial vessels are communicated is overgrown for several hours or days of the baby's life. Admission of the mother during pregnancy "Ibuprofen" in the 3rd trimester may cause premature closure of the duct. After all, prostaglandins, which block ibuprofen, inhibit the closure of the duct. If the duct is closed prematurely due to a lack of prostaglandins, the fetus may develop pulmonary hypertension, which often results in a failure of the right ventricle of the heart and early death.
At women on a background of reception "Ibuprofena" can develop a water shortage. For a child, this threatens with impaired renal function, which can develop into kidney failure. There is also a risk of severe and prolonged bleeding during childbirth caused by the anticoagulant effect of NSAIDs. And a decrease in the viscosity of the blood can be observed even against the background of low doses.
It is clear that such passions during pregnancy are unlikely to be caused by a single tablet of Ibuprofen taken from headache or toothache. Another thing is if the future mother at a later date will solve many of her problems with this drug. In the third semester of pregnancy, even forms for topical administration are dangerous, although in this case the absorption of the drug into the blood is less than in oral administration.
And yet, before asking for help with ibuprofen without special need, it is worth a hundred times to think about the possible consequences for themselves and the child. Doctors of "Ibuprofen" during pregnancy during this period prescribe only in serious situations that threaten the life and health of women, if there is no possibility to treat with even safer drugs. In this case, the course of treatment should be minimal to avoid the consequences of long-term use of the medication.
Do not relax and take "Ibuprofen" during pregnancy in the 2nd trimester. It's one thing if a future mother removes strong headache or toothache with ibuprofen, another thing is if she is treating any malaise with the drug. At pregnancy in general it is desirable to address to tablets less. For example, with cold and fever, tea with raspberry jam or a broth of currant twigs well helps. And you can cope with the headache and the same cold with lime or mint tea. From the pain in the teeth helps a solution of salt, and the muscular and joint pains subside, if a place of defeat to attach a leaf cabbage or plantain.
Course treatment "Ibuprofenom" can appoint a gynecologist if a woman has a threat of involuntary interruption of pregnancy due to the reduction of the walls of the uterus, caused by malfunctions in the hormonal background. It is shown in a period when the fetus is still unviable. This is a necessary measure for maintaining a pregnancy, which can be prescribed in the 2nd trimester.
But let's return to contra-indications for the use of Ibuprofen. Despite the fact that from the 14th week of pregnancy and up to 30 weeks of "Ibuprofen" is considered a relatively safe drug, not every woman can afford it. Exacerbation of gastrointestinal diseases, blood diseases, liver and kidney disorders, most likely, will become an obstacle to such treatment. And ignoring contraindications will lead to deterioration of the state of the future mother, which is very undesirable in pregnancy, when the load on the body is so great. A weakened organism can simply not cope with the mission entrusted to it, various vital organs will start to malfunction, and doctors can decide to deliberately terminate a pregnancy that threatens the life and health of a woman.