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Dufaston in Pregnancy

, medical expert
Last reviewed: 10.08.2022
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Let's talk about whether it is necessary to take dyufaston during pregnancy.

Unfortunately, many women have difficulties with conceiving and bearing a child. According to statistics, such problems are found among 15-20% of married couples. But it is necessary to give due to modern achievements in medicine, many such questions are successfully solved by the appointment of qualified appropriate treatment.

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Duphaston or morning after pregnancy: which is better?

If the body lacks natural progesterone, usually one of the medications is prescribed, which compensates for the deficiency of this vital hormone. The most popular are djufaston and morning after pregnancy. Let us analyze these medicines separately.

Dufaston in Pregnancy

Duphaston - a means for internal use, has progestagenic activity in relation to the mucous membrane of the uterus. Perfectly perceived by the body, does not affect the health of the liver, normalizes the state of the endometrioid tissue, does not interfere with the onset of the menstrual and ovulatory period, increases the chances of successful conception, reduces the risk of miscarriage and frozen pregnancy.

It differs from the morning period in that djufaston does not have a tranquilizing effect on the nervous system, it is not a tocolytic. Does not cause estrogenic, corticosteroid and anabolic effects on the body.

Unlike dyufastone, which has dydrogesterone in its composition, the drug morningol consists of an active substance of progesterone. It is a hormone formed in the yellow body, placenta and adrenal glands. Progesterone and dydrogesterone have a different chemical structure due to only one methyl group, so there are no significant differences in the effects of the drugs.

Utrozhestan has an advantage in the form of release: capsules can be taken orally, or in case of toxicosis and problems with the digestive system, instead of suppositories intravaginally.

Dufaston increases the resistance of brain tissue to damaging factors. It does not actually cause adverse reactions and does not have an androgenic effect.

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Duphaston and metopred during pregnancy

Metipred is a preparation of the hormone of the adrenal cortex of methylprednisolone. It is an active glucocorticosteroid, used in the process of pregnancy planning mainly as an inhibitor of male sex hormones, or as an immunosuppressant.

Immunodepressive properties of metipred allow the use of the drug and during the bearing of the child, with the threat of the probability of rejection of the fetus by too active protective forces of the body. Methylprednisolone artificially inhibits immunity, thereby contributing to the preservation of pregnancy.

Also, the important property metipreda in the presumed conception is a decrease in the drug the likelihood of the formation of adhesions in various inflammations. Metipred has an anti-inflammatory effect, in addition, it provides a balance of all types of metabolism - water, mineral, fatty, protein and carbohydrate.

Duphaston and metipred during pregnancy complement each other, creating a favorable background for the development and course of pregnancy, increasing the chances of a woman safely endure the child.

Divigel and Dyufaston in Pregnancy

Divigel and djufaston in pregnancy is a fairly common combination of drugs, because the necessary balance of progesterone and estrogens is very important for successful conception. The lack of progesterone is compensated by the appointment of dyufastone, and the deficiency of estradiol is replenished by the divergent.

Divigel - a preparation of estradiol, is available in the form of a dosed gel, which is applied a thin layer directly on the skin. When the substance is applied, the alcohol rapidly evaporates, and the hormone is absorbed into the skin, penetrating into the bloodstream. Such application of the agent allows to eliminate the action of enzymes on the drug during passage through the gastrointestinal tract, and also to avoid the initial stage of hepatic metabolism.

In the process of joint use of divulgium and dyufastone it is recommended to conduct a periodic blood test for the content of estrogens and progestogens.

Whether to drink djufaston at pregnancy?

Whether to drink djufaston at pregnancy, the doctor-gynecologist solves exclusively. In most cases, dydrogesterone, which is part of the drug, in the right doses contributes to the preservation and safe passage of pregnancy, leading to a normal content of progesterone in the blood.

Dyufaston can be appointed at the threat of abortion, for the prevention of miscarriage with artificial insemination and in vitro fertilization, especially if such cases have already occurred in women.

If dyufaston is prescribed and taken under the supervision of a specialist, it is possible and necessary to use it during pregnancy.

Effect of djufastone on pregnancy

Repeatedly conducted scientific researches once again confirm, that influence of djufaston on pregnancy basically favorable. This drug, as it were, "prepares the soil" for the successful conception, attachment and bearing of the unborn child.

The use of dyufastone significantly reduced the percentage of spontaneous interruptions of pregnancies in the first trimester, and also reduced the risk of morpho-functional disorders of the fetus and the maternal placenta due to various pathological processes.

The intake of additional doses of progesterone (dydrogesterone) in the body helps the placental shell in a timely manner to create a hormonal, oxygen and nutritional balance for the developing fetus. Due to this, babies, taken out against the background of taking the drug, have normal weight, physiological and mental development at birth.

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Frozen pregnancy with duftaston

The main functional purpose of dyufastone is to prevent the threat of spontaneous abortion and at any opportunity to preserve it.

When there are signs of a dead pregnancy, dyufaston is canceled for the natural disposal of the body from the traces of the failed process. By itself, this drug can not provoke the fading of the fetus, rather, on the contrary, it creates prerequisites for the normal course of pregnancy and the full development of the unborn child. Dyufaston is considered to be the No. 1 drug at threat of pregnancy, and this has been proved many times by leading world experts.

Dyufaston for abortion

Duphaston is a preparation of the hormone of the yellow body of the ovaries, the adrenal glands and the placenta of progesterone, which in no way is neither a contraceptive nor a means for aborting a pregnancy. Dydrogesterone is designed to preserve pregnancy and help cope with any threats of its interruption.

Duphaston with ectopic pregnancy

During the ectopic pregnancy, the fetal egg begins its development outside the uterus. With the progressive growth of the process, there is a risk of organ rupture, in which pregnancy develops.

When diagnosing ectopic pregnancy, all medications, including duftastone, are discontinued, and the amount of necessary surgical intervention is determined.

Duphaston, as a medical product, does not have a provocative effect on the development of ectopic pregnancy. Its development is determined by completely different factors, for example, obstruction of the fallopian tubes, the presence of inflammatory processes in the reproductive organs, the adhesion process or anomalies in the structure of the genital organs.

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Dufaston in pregnancy with a bladder

With the onset of pregnancy, women may notice the appearance of brownish discharge. At 1-2 weeks of pregnancy this can be explained by an attempt by the body to reorganize into a new state when there is a radical change in the hormonal background.

But do not forget that spotting can be a terrible symptom of a brewing miscarriage or a sharp drop in the level of hormones in the blood. At the slightest opportunity to save pregnancy, a woman will be prescribed dyufaston, or another progestagenic drug to stop the threat of spontaneous abortion.

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Dyufaston with myoma during pregnancy

How does dyufaston affect a benign tumor, in particular, myoma? This problem has not been sufficiently studied. However, specialists are inclined to believe that progesterone, taken in excess of the therapeutic dosage, favors an increase in the already existing uterine fibroids. At the same time, progesterone preparations in small dosages, on the contrary, depress its growth and development.

It should be noted that dyufaston in case of myoma during pregnancy should be prescribed only strictly individually, according to the data and indications, by comparing the risk of complications and possible benefits for the normal course of pregnancy.

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Is Dufaston harmful during pregnancy?

Despite some isolated negative comments about treatment with dyufastone, which can be found mostly in social networks, experts still consider the drug to be absolutely safe and harmless in pregnancy. Scientific statistics, for many years of using dyufastone in gynecology and reproductive medicine, does not describe a single case of the negative effect of the drug on the process of conception and bearing of the fetus. Dyufaston is absolutely not harmful during pregnancy, and sometimes it is just necessary for the normal development of the baby. Naturally, when taking is indispensable is the control of the hormonal level in the blood of a pregnant woman.

Duphaston instructions for pregnancy

Duphaston, when applied internally, has a selective effect on the endometrium, while also preventing the existing danger of excessive overgrowth of the endometrium or malignancy of healthy cells due to excess estrogen.

Dyufaston does not have contraceptive abilities, does not inhibit the process of ovulation and does not disrupt the menstrual process.

The drug is easily absorbed in the gastrointestinal tract, the highest concentration is observed within two hours after taking the pill. Metabolism occurs in the liver, is excreted from the body mainly through the kidneys, the withdrawal period of up to three days.

The scheme of reception of djufaston at pregnancy:

  • with endometriotic growth of tissues take 1 tablet 2 to 3 times a day, from the last day of menstruation on the 25th day of the cycle, or permanently;
  • if the luteal phase is insufficient, 1 tablet a day from the time of ovulation to day 25 of the cycle. It is recommended to take 6 months in a row, and also, with a safe conception, during the first trimester of pregnancy;
  • when a threat of spontaneous abortion is taken 4 tablets at one time, then 1 tablet 3 times a day until the threat ends;
  • in the treatment and prevention of uterine bleeding take 1 tablet 2 times a day for a week.

The dose of dyufastone during pregnancy is determined exclusively by the doctor-gynecologist on the basis of the diagnosis, clinical symptoms and mandatory blood test for the content of estrogenic and progestogen hormones.

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How do I take Dufaston during pregnancy?

If djufaston has been appointed or nominated even before approach of pregnancy its reception continue without fail up to 16 weeks. The dose is calculated by the doctor, based on the level of progesterone in the patient's blood.

If the future mother did not use progesterone preparations before pregnancy, and then it turned out that the level of the hormone decreased for any reason, then in this situation also prescribe dyupaston in accordance with its blood content, up to 24-25 weeks of pregnancy.

How much to drink djufaston at pregnancy?

About the duration of doufaston during pregnancy, your doctor will tell you, based on the results of the tests and the condition of the pregnant woman. Usually the drug is prescribed in the first trimester of pregnancy for successful attachment of the fetus and the formation of the placenta. Further, according to the indications, it is possible to use dufaston in the second trimester for the prevention and treatment of the threat of miscarriage. After 36 weeks of gestation, the drug is discontinued.

What should I do if I missed taking dyufastone during pregnancy?

If during the treatment with dyufastone you accidentally missed one reception (forgot, it did not work, or for another reason), it is recommended to drink the taken dose of the drug in the next 6 hours. If more than 6 hours have elapsed since the required admission, then you do not need to take an additional pill, just keep following the usual prescribed pattern of drug use. And try not to forget about the need to take medicines in the future!

How to cancel djufaston at pregnancy?

The abolition of djufastone during pregnancy is carried out gradually, with a slow decrease in the dose of the drug. For example, if a pregnant woman took 2 tablets a day, then this dosage is reduced to 1.5 tablets, and a week later to 1 tablet. So taking the medicine gently reduces to zero.

Cancellation of the drug is possible only with the recommendation of the treating doctor, with normal hormonal levels in the patient's blood. The scheme of discontinuation may last several weeks.

It should be remembered that a sharp cancellation of any hormonal drugs can lead to irreversible consequences.

Side Effects of Dufaston in Pregnancy

Side effects of dyufastone during pregnancy are quite rare and, as a rule, are eliminated by correcting the dosage of the drug. When used in small doses, diffuse bleeding from the uterus is possible, which occur after an increase in dosage. Perhaps the increase and soreness of the mammary glands, spastic headaches, pain in the epigastric region. Less often - skin rashes as a consequence of allergies, or accumulation of fluid in the tissues, swelling of the legs, hands. There may be an increase or decrease in sexual desire.

Overdose of duhfaston in pregnancy

At this time, cases of a duleston overdose during pregnancy have not been documented. With a single random application of the drug in a significant dosage, it is necessary to rinse the stomach with plenty of water, provide the patient with peace of mind until the discomfort disappears. Possible additional prescribing of medicines acting on the current clinical symptoms of poisoning. Special drugs that render harmless in the body of dyufaston do not exist.

Contraindications to the use of djufaston in pregnancy

The main contraindication to the use of djufaston in pregnancy is the propensity to allergic reactions to any of the constituents of the drug. You should be careful with increased individual sensitivity of the body.

Do not prescribe progesterone preparations to patients with rare diseases of Rotor and Dabin-Jones, with severe diseases and violations of the liver, with malignant neoplasms of the mammary glands and genitals. With care, patients are treated with active vascular thromboembolism, as well as with severe thrombophlebitis and a tendency to thrombosis.

Usually stop taking dyufastone from the 36th week of pregnancy, or with a frozen and ectopic pregnancy, also with the appearance of bleeding of an unexplained genesis.

Dyufaston in the planning of pregnancy

Widely used dyufaston in the planning of pregnancy. After all, progesterone prepares the endometrium for implantation of the egg, accelerates its development, improves the nutrition of tissues, reduces the tone of the uterus. It has also been shown to have a positive effect on the immune interaction of the future mother and embryo. The drug is prescribed for infertility on the background of the lack of progesterone produced in the body. This condition is called deficiency of the luteal phase of the menstrual cycle.

The usual course of taking the drug during the planning is at least six months.

Take, as a rule, 1 tablet a day from the moment of ovulation and until the 25th day of the menstrual cycle.

With a favorable onset of pregnancy, taking the drug continues to avoid possible problems: miscarriage or fading of the fetus.

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Duphaston in early pregnancy

Duphaston-containing synthetic progesterone plays one of the most important roles in the early stages of pregnancy. First of all, he helps a pregnant woman to bear a child. The drug relaxes the uterine musculature and reduces the strength and frequency of its contractions, which many times reduces the risk of premature spontaneous abortion.

In addition, dyufaston blocks the immune response of the female body, which avoids the destruction of the developing fetus by immune agents.

During the period of gestation, the drug should be administered under the mandatory control of the hormonal balance in the body and the basal temperature.

Dyufaston in late pregnancy

The duration of use of dyufastone directly depends on the course of pregnancy. As a rule, it is used until 16-20 weeks. In this period, the formation of the placental layer is completed, which independently starts the synthesis of progesterone. Sometimes, according to the indications, the drug is delayed, but after 36 weeks, the appointment is canceled in any case.

Duphaston late in pregnancy does not have a teratogenic effect on the fetus.

Does Dufaston help to keep pregnancy? Of course, yes. It is not for nothing that progesterone, a synthetic analogue of which is part of dyufastone, is called the "female hormone of pregnancy". It not only contributes to the preservation of the fetus, but also supports its nutrition and development.

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Reviews of dyuustone during pregnancy

You can read a lot of comments about taking dufastona. Reviews are very diverse, sometimes even diametrically opposed in opinions.

About 30% of women taking this drug are absolutely sure that it was he who allowed them to keep their pregnancy. Approximately the same number of women argue about the advisability of appointing a doctor dyufastone, while not calling its effectiveness. Statements by women that the drug could not prevent a spontaneous abortion, occupy the third position of the list. The remaining pregnant believe that it is possible to become pregnant and bear fruit without the use of any hormonal means, including djufastona.

Reviews of doctors about djufastone during pregnancy

Dufaston is used for successful development of pregnancy for at least half a century. Throughout this time, the drug was studied, tested, and accumulated valuable experience in its use in gynecology and reproductive medicine. Dufaston has established itself as a highly effective progesterone analog, with a minimum of adverse events and contraindications.

The present specialists-reproductologists and gynecologists-endocrinologists unequivocally consider the drug effective and indispensable in many situations. Its usefulness for maintaining pregnancy is undeniable.

Negative responses, sometimes found in comments, are more likely to belong to incompetent, or under-qualified doctors who have little experience and lack of information.

If your treating gynecologist prescribes hormonal drugs for you, do not be afraid of it - the health and safety of your unborn child is at stake.

However, do not take these medications yourself, they should be prescribed by a doctor. Follow the recommendations of a specialist, do not be afraid to take djufaston during pregnancy, and let the period of bearing a baby will not bring you any trouble.

Attention!

To simplify the perception of information, this instruction for use of the drug "Dufaston in Pregnancy" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

Translation Disclaimer: For the convenience of users of the iLive portal this article has been translated into the current language, but has not yet been verified by a native speaker who has the necessary qualifications for this. In this regard, we warn you that the translation of this article may be incorrect, may contain lexical, syntactic and grammatical errors.

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