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Causes of miscarriage

The main causes of miscarriage are associated with problems in the hormonal sphere of women, metabolic features and immune disorders.

In addition, infectious diseases, the anatomical abnormalities of the reproductive organs and various congenital diseases play an important role in the mechanism of the development of this pathology. Often, the reasons lie in the unhealthy image of a woman and her bad habits, as well as in bad ecology, which can lead to impaired development of the fetus.

At the same time, specialists admit that in almost half of cases of spontaneous termination of pregnancy, the true causes of miscarriage can not be clarified.

Fetal egg detachment in early pregnancy

The term detachment implies two conditions: immediate detachment (early stages) and critical condition (middle or end of pregnancy). In the first case, it is an alarming signal about a possible miscarriage.

Paternal causes of non-pregnancy

Paternal causes of miscarriage play a lesser role than maternal ones, with the exception of chromosomal pathology. However, according to many researchers, husbands of women with habitual miscarriage have a high percentage of spermatogenesis disorders: oligospermia, polyspermia, teratospermia and leukocytospermia.

Maternal extragenital diseases and premature termination of pregnancy

Extragenital diseases of the mother are one of the most common causes of premature termination of pregnancy. The high-risk group for miscarriage primarily consists of women with cardiovascular diseases, hypertension, chronic kidney, liver, and intestinal diseases.

Factors of pregnancy termination

Among the factors of pregnancy termination, pregnancy complications occupy a large place: toxicosis in the second half of pregnancy, abnormalities of placental attachment, premature detachment of the placenta, abnormal position of the fetus.

Uterine pathology as a cause of habitual miscarriage

Malformations of the uterus play a major role in the etiology of habitual miscarriage, especially in the termination of pregnancy in the second and third trimesters. The frequency of malformations of the uterus in the population is only 0.5-0.6%.

Disorders of the hemostasis system and pregnancy failure

The state of the hemostasis system determines the course and outcome of pregnancy for the mother and fetus. In recent years, there have been a significant number of publications indicating the major role of thrombophilic complications in habitual miscarriage, intrauterine fetal death, placental abruption, the development of eclampsia, and intrauterine growth retardation.

Antiphospholipid syndrome and miscarriage of pregnancy

Antiphospholipid syndrome is the most common cause of thrombophilic complications and associated habitual pregnancy loss. A distinction is made between primary antiphospholipid syndrome and secondary - in the presence of an autoimmune disease (most often systemic lupus erythematosus).

Immunologic causes of non-pregnancy

Over the course of several decades, with the emergence of new methodological possibilities in immunology, the problem of immunological relationships between mother and fetus has received the closest attention.

Bacterial causes of non-pregnancy

In recent years, studies have appeared that show the role of disturbances in the normal microflora of the genital tract in premature termination of pregnancy.

Coxsackie virus infection and pregnancy failure

A high risk of vertical transmission of enteroviruses, primarily Coxsackie viruses, has been established in the presence of spontaneous miscarriages, stillbirths, and complications such as threatened termination of pregnancy in the mother.

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