Lindax for weight loss

Lindax is widely used in treatment regimens for obesity, since it has an anorexigenic effect.

Indications Lindax for weight loss

Lindax is used:

• when eating (alimentary) obesity, if the body mass index (BMI) is above 30 kg per m²;
• when eating (alimentary) obesity, if the body mass index is above 27 kg per m² and there are complications associated with excess weight (for example, type 2 diabetes mellitus, or signs of dyslipoproteinemia).

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Release form

Lindax is produced in tight capsules based on gelatin, yellow, with a brownish lid and the inscription "10" or "15".

In capsules there is a light colored powdery substance.

The active ingredient is sibutramine, in an amount of 10 or 15 mg.

Cardboard packaging usually contains three or nine blister plates, 10 capsules in each plate.

The names of Lindax's analogs:

• Goldline (capsules).
• Meridia (capsules).
• Slimy (capsules).

Pharmacodynamics

Lindax has an anorexigenic effect, increasing the feeling of satiety. The effect of the drug is achieved under the influence of residual products of the active ingredient exchange - primary and secondary amines, which inhibit the reverse capture of monoamines (they are norepinephrine and serotonin).

Simultaneously with an increase in the number of neurotransmitters inside the synapses, adrenoreceptors and central serotonin receptors are stimulated. The result of such processes is a decrease in appetite and an increase in energy efficiency (fat consumption).

Stimulation of β-adrenergic receptors helps to reduce the severity of brown lipid tissue.

The active ingredient sibutramine does not provoke the yield of monoamines, does not inhibit MAO.

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Pharmacokinetics

Absorption of the active ingredient is complete, with a pronounced intensity of metabolism during the primary exposure to the liver. When Lindax is administered orally in an amount of 20 mg, the limit of the active ingredient is found after 80 minutes, and the maximum content of active metabolic products is 180 minutes later.

The connection of sibutramine and proteins is 97%, and the active exchange products - 94%. Distribution in tissues is satisfactory.

Metabolism occurs in the liver with the formation of mono-dismethyl and di-dimethyl variants of active metabolic products.

The half-life of the active ingredient can be 70 minutes, and the active exchange products - 14-16 hours.

Excretion is carried out through the kidneys.

Kinetic properties can not change in the presence of insufficient kidney function, and also can not depend on the severity of obesity, gender and age characteristics.

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Dosing and administration

Lindax is prescribed according to an individual scheme, taking into account the reaction to the drug and the effect of its administration.

Normally, Lindax is drunk 1 time per day, in the morning, before breakfast or during it. The capsule is taken as a whole and is washed down with water, tea or compote.

The initial amount of the drug is 10 mg. If the effect of the drug is not enough (for example, the patient loses less than 2 kg of excess weight per month), then the dosage can be increased to 15 mg. If, in this case, the effect of treatment is weak, the further designation of Lindax is considered to be irrational.

Also, the drug is stopped after 3 months in the event that during this time the patient did not get rid of 5% of his weight.

Receiving Lindax is terminated if the patient has an increase in weight over 3 kg.

The total duration of Lindax is no more than 2 years, since longer treatment with the drug has not been tested for safety and efficacy.

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Use Lindax for weight loss during pregnancy

Lindax under no circumstances can be prescribed to pregnant and lactating women. The listed conditions are considered a contraindication to the use of the medication.

Contraindications

Lindax has a sufficiently large number of contraindications, which must be paid attention before starting treatment with the drug.

Lindax is not appointed:

• if the causes of obesity are other factors, except food;
• with serious eating disorders in the form of anorexia or bulimia;
• with mental disorders;
• in the chronic form of generalized teak;
• in combination with medicines, MAO inhibitors, serotonin reuptake inhibitors, barbiturates, tryptophan-based drugs and other drugs that reduce weight;
• in diseases of the heart and blood vessels (myocardial ischemia, stroke, heart disease, rhythm disturbances, occlusion of peripheral vessels);
• with an uncontrolled increase in blood pressure with an index exceeding 145/90 mm Hg. P.
• with hyperthyroidism;
• with severe liver disorders;
• with benign prostate enlargement;
• with pheochromocytoma;
• persons suffering from alcohol, drug, or drug dependence;
• with increased intraocular pressure, the closed-angle form of glaucoma;
• when carrying a child and breastfeeding;
• children under 18;
• elderly patients from 65 years of age;
• with hypersensitivity to the composition of Lindax.

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Side effects Lindax for weight loss

Undesirable side effects usually manifest themselves at the initial stage of treatment (during the first month). With further administration of the drug such symptoms become less noticeable.

Most often, patients complain of such side effects:

• sleep disturbances, headaches, flavors, changes in sensitivity in the limbs;
• increased heart rate, increased blood pressure, redness of the skin, a feeling of heat;
• thirst, lack of appetite, difficulty with defecation, less often - nausea;
• increased sweating, recurrence of hemorrhoids;
• rarely - swelling, pain in the abdomen, irritability, convulsions.

Overdose

Information on the likelihood of Lindax overdose received little. It is assumed that this condition may be accompanied by an increase in the severity of adverse symptoms.

A special substance with the opposite action, which could be used as an antidote, does not exist.

Treatment should be aimed at eliminating excess sibutramine in the body:

• reception of enterosorbents;
• gastric lavage;
• at a hypertensia and disturbance of a warm rhythm - reception of β-adrenoblockers.
• It is not known whether there is an effect of hemodialysis or forced diuresis.

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Interactions with other drugs

The combination of Lindax with ketoconazole, erythromycin, cyclosporins and troleandomycin can lead to tachycardia and ECG changes (QT prolongation).

The combination of Lindax with rifampicin, macrolides, phenytoin, dexamethasone, phenobarbital, carbamazepine can provoke an acceleration of sibutramine metabolism.

The combination of Lindax with antidepressants, antimigrenous drugs, strong analgesics and dextromethorphan can lead to the development of serotonin syndrome.

Lindax does not affect the effectiveness of oral contraceptives.

No negative interactions were found in the joint use of Lindax and ethyl alcohol.

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Storage conditions

Lindax is kept in a place difficult to reach for children, with an ordinary temperature not exceeding + 30 ° C.

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Shelf life

The shelf life of the drug is up to 2 years.

Lindax's medication is appropriate only when the application of dietary nutrition and metered exercise does not bring the expected result (weight loss is less than 5 kg in three months).

Lindax is used only under the strict supervision of a doctor who has the qualifications and practice of treating obese patients. Along with taking the drug, mandatory conditions should remain such items as diet, exercise, the right combination of rest and work.

Lindax Reviews

Lindax is a medicine that doctors use to relieve the condition of obese patients. However, this drug has long been interested in those who want to get rid of excess kilograms, and at the same time does not have such a diagnosis as obesity.

Can Lindax be taken in cases where the excess weight and BMI are not menacing to human health? Will this drug do any harm? What do experts think about this? What feedback do people leave on Lindax?

Doctor's comments

Lindax's preparation is not such an inoffensive remedy, as many people think about it. It is not for nothing that this medicine refers to those that are dispensed only by prescription.

Lindax has a lot of side effects, and many of them represent a serious danger to health. That is, having solved the problem of excess weight, you can significantly "undermine" the health of the whole organism.

So, often Lindax is accompanied by disorders of the nervous system and psyche. There are cases when patients who have been treated with a drug for a long time, made themselves suicidal - their attitude to reality changed so much. Although at the beginning of treatment, the side symptoms were expressed only in a small sense of anxiety and general discomfort.

In addition, there is a great strain on the heart when taking the medication:

• the pulse becomes faster;
• the pressure rises;
• the vessels expand;
• a person begins to feel how much his heart beats (especially at night, at rest).

Lindax also affects the digestive system. With the suppression of appetite, constipation, thirst, sometimes - nausea.

Women can break the monthly cycle, abdominal pains appear.

Considering the listed unpleasant symptoms accompanying treatment with Lindax, doctors do not advise taking it without a prescription and without special testimony. In addition, Lindax is prescribed exclusively for alimentary (food) obesity. If excess weight is the cause of hormonal disorders, or other pathological conditions, then in such cases, Lindax is uniquely contraindicated.

Reviews thin

The testimonials of people who have already tried Lindax's action are very different. And in this there is nothing strange, because all the organisms are different, and react differently to the drug, and the reasons for excess weight can not be the same for all.

Those who previously suffered from obesity and took Lindax as prescribed by the doctor, often note the effectiveness of the drug. However, they all pay attention to the fact that taking the medication must necessarily be combined with dieting and doing all possible physical exercises. As a rule, the regime of the day and food is controlled by the attending physician, dietician and doctor LFK.

But in many cases, Lindax is accepted without the knowledge of a medical specialist. In such situations, opinions are divided:

• most users believe that Lindax really helps to lose weight, but - the number of side effects that occurs during treatment, darkens all the joy of losing weight; in addition, most of the kilograms after losing weight still returns;
• fewer users note the enthusiasm for taking Lindax and are trying to undergo treatment with the drug again.

So how do you: take or not take Lindax for weight loss, because reviews about the drug are so contradictory?

The answer is unequivocal: if the drug is prescribed by a doctor, take Lindax under his supervision. If you yourself want to undergo a course of treatment with the drug, and do not harm your health, listen to the following tips:

• go through a comprehensive examination - diagnosis of the reasons for your excess weight;
• take the necessary tests to know exactly what is preventing you from losing weight;
• Visit a nutritionist who will review your diet and pay attention to errors or improperly formulated rations;
• visit the gym or fitness center, where you will be provided with a personal trainer: it is not necessary to engage with him constantly (although it is desirable), sometimes there is enough a couple of sessions with a specialist so that in the future you can qualitatively deal with yourself.

If, according to the results of the diagnosis, you will still be shown Lindax reception, then it is necessary to pass the prescribed course, but under the supervision of the doctor. Only in this case reviews about Lindax can be entirely positive.